Natural remedies for reducing anxiety and stress
5th Sep, 2023

Natural remedies for reducing anxiety and stress


Anxiety is your body’s natural reaction to stress or discomfort, marked by feelings of fear, dread or unease (1).

While these feelings often pass as the stressor subsides, for some, anxiety persists and intensifies, leading to overwhelming fear, restlessness, worry, irritability, disrupted sleep, and physical symptoms such as muscle tension and heart palpitations (2,3).

Various factors contribute to anxiety, including genetics, work stressors, life-altering events, family or relationship issues, past traumas, physical health issues, and personality traits such as low self-esteem and perfectionism (1,2,3).

Fortunately, there are natural remedies that can help you increase your resilience to anxiety and stress.

GABA

Gamma-aminobutyric acid (GABA), an amino acid, functions as an inhibitory neurotransmitter that promotes relaxation and slows brain activity (4).

It helps regulate nerve cell function and may relax your muscles, reduce insomnia, and calm anxiety (4,5).


Ashwagandha

Ashwagandha is an adaptogenic herb that has been used in traditional medicine to promote relaxation and reduce stress and anxiety (6,7,8). Adaptogens are substances that help your body adapt to stress.

It is especially useful when morning cortisol levels are high, which may feel like anxiety in the morning or dreading the day ahead.


B vitamins

B vitamins help combat stress and stabilise your mood (9,10).

Vitamin B6 is important for the synthesis of neurotransmitters, including serotonin, dopamine, and GABA that regulate mood and maintain a healthy nervous system (11).

Vitamin B12 is important for reducing chronic stress and anxiety. It helps improve your concentration and energy levels and allows your nervous system to function adequately (12,13).


Chamomile

Chamomile, particularly tea, has been used for centuries as a natural remedy to promote relaxation and ease anxiety (14,15).

The calming effects of chamomile may be due to the flavonoid apigenin, which binds to benzodiazepine receptors in the brain, inducing a relaxing effect and alleviating feelings of anxiety (16).


GOS

Galacto-oligosaccharides (GOS) are a type of prebiotic fibre found in certain foods and dietary supplements.

They promote the growth of beneficial gut bacteria that aid in producing serotonin, impacting mood and anxiety (17).

The gut-brain axis is a communication network between the gut and brain that allows the gut microbiota (the microorganisms residing in the gut) to influence your emotions, mood, and stress response (18).

By promoting beneficial gut bacteria and supporting a balanced gut environment, GOS may contribute to mood regulation and a more adaptive stress response, which is critical for managing anxiety (17,18,19).


Holy basil

Holy basil, also known as Tulsi, boasts a rich history in traditional medicine like Ayurveda (20).

As an adaptogen, it enhances your resilience to stress and regulates cortisol levels, thereby contributing to anxiety relief (20,21).

It also interacts with neurotransmitters, including serotonin, dopamine and GABA that are involved in enhancing mood and inducing calmness (22,23).  


Kava

Kava, a plant-based drink, is renowned for its ability to promote relaxation and reduce stress and anxiety (24).

It contains kavalactones that interact with brain neurotransmitters, such as GABA, creating a calming effect (25).


L-Theanine

L-Theanine, an amino acid found in tea leaves—especially in green tea—is known for its ability to promote relaxation without causing drowsiness (26,27).

It also promotes alpha brain wave activity, leading to a state of relaxed alertness and enhanced focus and attention (28,29).


Lavender

Lavender is a calming herb known to reduce anxiety and help relax the body (30,31).

It is often used in various forms, such as essential oils, sachets, or in teas, to help create a calming environment and relieve symptoms of anxiety, like nervousness, headaches and muscle pain (30,32).


Lemon Balm

Lemon balm may alleviate anxiety by interacting with GABA receptors, promoting a relaxing and calming effect (33,34).

It also helps reduce anxiety by influencing neurotransmitters like serotonin and dopamine, leading to a calm state (34,35).


Magnesium

Magnesium is a mineral that has calming effects and can increase GABA levels in the brain, reducing the excitatory activity of glutamate, a neurotransmitter that is associated with anxiety (36,37).


Reishi

Reishi, a medicinal mushroom, acts as an adaptogen, helping your body better adapt to stress and alleviate anxiety (38,39).

It contains compounds, such as triterpenes and polysaccharides, that may promote relaxation and ease anxiety (39,40).


Rhodiola

Rhodiola rosea is an adaptogenic herb that has been traditionally used to help the body cope with stress and improve resilience (41,42).

It regulates the body's stress response through the hypothalamic-pituitary-adrenal (HPA) axis, which could help alleviate anxiety by managing how the body reacts to stress (41,42).

Rhodiola may impact neurotransmitter levels, including serotonin, dopamine, and norepinephrine, which play roles in mood regulation (42,43).


Zinc

Zinc, along with vitamin B6 and magnesium, helps to regulate GABA and serotonin, neurotransmitters that influence mood and anxiety (44,45).

 

9 lifestyle tips to alleviate stress and anxiety

Aromatherapy

Aromatherapy uses essential oils with calming properties to promote relaxation, boost your mood and alleviate anxiety. 

Scents to use for anxiety include bergamot, lavender, sandalwood, sweet orange and ylang ylang.

CBT

Cognitive behaviour therapy (CBT), a type of talk therapy, can help you understand and change the thought patterns and behaviours that contribute to anxiety.

It provides you with practical tools to help you manage anxiety and confront triggers more confidently.

Cold water immersion

Exposure to cold water triggers a response known as the diving reflex (50). This reflex causes your body to conserve oxygen by slowing your heart rate and redirecting blood flow to vital organs (50). This process may induce a calming effect and help reduce anxiety symptoms (51). 

Deep Breathing

Practicing deep, slow breathing techniques that involve your diaphragm—a muscle beneath your lungs—can soothe your nervous system, alleviate stress, and ease symptoms of anxiety (52).

EFT

Emotional Freedom Techniques (EFT) involves tapping on specific points on your body while thinking or talking about your worries or fears. This process can help you release stress and change how you think about your concerns (53,54).

Exercise

Regular physical activity, such as walking, jogging, swimming, or yoga, can reduce cortisol levels, regulate the stress response, and release endorphins that alleviate pain and anxiety (55,56). 

By concentrating on the movements and sensations of exercise, you can redirect your attention away from anxious thoughts.

Exercise also influences neurotransmitter levels, including serotonin and dopamine, which are crucial for mood regulation (55,56).

Journaling

Writing down your thoughts and feelings can help you process emotions and gain insights into your anxiety triggers (57,58).

Meditation

Meditation can help to relieve anxiety symptoms, helping you to feel more at ease (59,60).

Techniques like mindfulness meditation help you focus on the present moment, reducing anxious thoughts and promoting relaxation (59,60).

Nutrition

A healthy diet that provides adequate amounts of protein, carbohydrates, fat, fluids, and nutrients is associated with a reduced risk of anxiety (61,62).

Healthy eating patterns, such as the Mediterranean diet, are linked to improved mental well-being compared to less healthy options such as the Western diet (61,62).

Key-takeaway

There are numerous natural remedies and lifestyle strategies that can enhance resilience to stress and anxiety.

These approaches focus on regulating neurotransmitters, promoting relaxation, and developing resilience to stressors, ultimately contributing to a more balanced and calmer state of mind.

A balanced diet, regular exercise, stress management techniques, and, if necessary, professional guidance should all be considered when addressing anxiety. If you are considering making any significant changes to your diet or supplementation, it's advisable to consult with a healthcare professional.

Loading...
References
1Penninx BW, Pine DS, Holmes EA, Reif A. Anxiety disorders. Lancet. 2021 Mar 6;397(10277):914-27.
2Ströhle A, Gensichen J, Domschke K. The Diagnosis and Treatment of Anxiety Disorders. Dtsch Arztebl Int. 2018 Sep 14;155(37):611-20.
3Szuhany KL, Simon NM. Anxiety Disorders: A Review. JAMA. 2022 Dec 27;328(24):2431-45.
4Savage K, Firth J, Stough C, Sarris J. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytother Res. 2018 Jan;32(1):3-18.
5Hepsomali P, Groeger JA, Nishihira J, Scholey A. Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020 Sep 17;14:923.
6Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019 Sep;98(37):e17186.
7Pratte MA, Nanavati KB, Young V, Morley CP. An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera). J Altern Complement Med. 2014 Dec;20(12):901-8.
8Speers AB, Cabey KA, Soumyanath A, Wright KM. Effects of Withania somnifera (Ashwagandha) on Stress and the Stress- Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021;19(9):1468-95.
9Mahdavifar B, Hosseinzadeh M, Salehi-Abargouei A, Mirzaei M, Vafa M. Dietary intake of B vitamins and their association with depression, anxiety, and stress symptoms: A cross-sectional, population-based survey. J Affect Disord. 2021 Jun 1;288:92-8.
10Young LM, Pipingas A, White DJ, Gauci S, Scholey A. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and 'At-Risk' Individuals. Nutrients. 2019 Sep 16;11(9):2232.
11Field DT, Cracknell RO, Eastwood JR, Scarfe P, Williams CM, Zheng Y, et al. High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression. Hum Psychopharmacol. 2022 Nov;37(6):e2852.
12Gharibpoor F, Ghavidel-Parsa B, Sattari N, Bidari A, Nejatifar F, Montazeri A. Effect of vitamin B12 on the symptom severity and psychological profile of fibromyalgia patients; a prospective pre-post study. BMC Rheumatol. 2022 Sep 1;6(1):51.
13Sahu P, Thippeswamy H, Chaturvedi SK. Neuropsychiatric manifestations in vitamin B12 deficiency. Vitam Horm. 2022;119:457-70.
14Hieu TH, Dibas M, Surya Dila KA, Sherif NA, Hashmi MU, Mahmoud M, et al. Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep quality: A systematic review and meta-analysis of randomized trials and quasi-randomized trials. Phytother Res. 2019 Jun;33(6):1604-15.
15Mao JJ, Xie SX, Keefe JR, Soeller I, Li QS, Amsterdam JD. Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial. Phytomedicine. 2016 Dec 15;23(14):1735-42.
16Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Rep. 2010 Nov 1;3(6):895-901.
17Johnstone N, Milesi C, Burn O, van den Bogert B, Nauta A, Hart K, et al. Anxiolytic effects of a galacto-oligosaccharides prebiotic in healthy females (18-25 years) with corresponding changes in gut bacterial composition. Sci Rep. 2021 Apr 15;11(1):8302.
18Johnstone N, Dart S, Knytl P, Nauta A, Hart K, Cohen Kadosh K. Nutrient Intake and Gut Microbial Genera Changes after a 4-Week Placebo Controlled Galacto-Oligosaccharides Intervention in Young Females. Nutrients. 2021 Dec 8;13(12):4384.
19Schmidt K, Cowen PJ, Harmer CJ, Tzortzis G, Errington S, Burnet PW. Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Psychopharmacology (Berl). 2015 May;232(10):1793-801.
20Jamshidi N, Cohen MM. The Clinical Efficacy and Safety of Tulsi in Humans: A Systematic Review of the Literature. Evid Based Complement Alternat Med. 2017;2017:9217567.
21Bhattacharyya D, Sur TK, Jana U, Debnath PK. Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorders. Nepal Med Coll J. 2008 Sep;10(3):176-9.
22Cohen MM. Tulsi - Ocimum sanctum: A herb for all reasons. J Ayurveda Integr Med. 2014 Oct-Dec;5(4):251-9.
23Lopresti AL, Smith SJ, Metse AP, Drummond PD. A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress. Front Nutr. 2022 Sep 2;9:965130.
24Sarris J, Byrne GJ, Bousman CA, Cribb L, Savage KM, Holmes O, et al. Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study. Aust N Z J Psychiatry. 2020 Mar;54(3):288-97.
25Smith K, Leiras C. The effectiveness and safety of Kava Kava for treating anxiety symptoms: A systematic review and analysis of randomized clinical trials. Complement Ther Clin Pract. 2018 Nov;33:107-17.
26Hidese S, Ogawa S, Ota M, Ishida I, Yasukawa Z, Ozeki M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019 Oct 3;11(10):2362.
27Sarris J, Byrne GJ, Cribb L, Oliver G, Murphy J, Macdonald P, et al. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial. J Psychiatr Res. 2019 Mar;110:31-7.
28Baba Y, Inagaki S, Nakagawa S, Kaneko T, Kobayashi M, Takihara T. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study. J Med Food. 2021 Apr;24(4):333-41.
29Williams JL, Everett JM, D'Cunha NM, Sergi D, Georgousopoulou EN, Keegan RJ, et al. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Plant Foods Hum Nutr. 2020 Mar;75(1):12-23.
30Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019 Dec;65:153099.
31Malcolm BJ, Tallian K. Essential oil of lavender in anxiety disorders: Ready for prime time? Ment Health Clin. 2018 Mar 26;7(4):147-55.
32Koulivand PH, Khaleghi Ghadiri M, Gorji A. Lavender and the nervous system. Evid Based Complement Alternat Med. 2013;2013:681304.
33Ghazizadeh J, Sadigh-Eteghad S, Marx W, Fakhari A, Hamedeyazdan S, Torbati M, et al. The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis. Phytother Res. 2021 Dec;35(12):6690-705.
34Scholey A, Gibbs A, Neale C, Perry N, Ossoukhova A, Bilog V, et al. Anti-stress effects of lemon balm-containing foods. Nutrients. 2014 Oct 30;6(11):4805-21.
35Stojanović NM, Mladenović MZ, Randjelović PJ, Radulović NS. The potential of lemon balm (Melissa officinalis L.) essential oil as an anti-anxiety agent - is the citronellal the activity carrier? J Ethnopharmacol. 2023 Oct 5;314:116661.
36Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. 2017 Apr 26;9(5):429.
37Kirkland AE, Sarlo GL, Holton KF. The Role of Magnesium in Neurological Disorders. Nutrients. 2018 Jun 6;10(6):730.
38Ahmad R, Riaz M, Khan A, Aljamea A, Algheryafi M, Sewaket D, et al. Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties. Phytother Res. 2021 Nov;35(11):6030-62.
39Singh R, Dhingra GS, Shri R. Evaluation of Antianxiety Potential of Four Ganoderma (Agaricomycetes) Species from India in Mice. Int J Med Mushrooms. 2016;18(11):991-98.
40Valverde ME, Hernández-Pérez T, Paredes-López O. Edible mushrooms: improving human health and promoting quality life. Int J Microbiol. 2015;2015:376387.
41Cropley M, Banks AP, Boyle J. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-9.
42Ivanova Stojcheva E, Quintela JC. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence. Molecules. 2022 Jun 17;27(12):3902.
43Anghelescu IG, Edwards D, Seifritz E, Kasper S. Stress management and the role of Rhodiola rosea: a review. Int J Psychiatry Clin Pract. 2018 Nov;22(4):242-52.
44Azargoonjahromi A. A systematic review of the association between zinc and anxiety. Nutr Rev. 2023 Jun 26:nuad076.
45Cope EC, Levenson CW. Role of zinc in the development and treatment of mood disorders. Curr Opin Clin Nutr Metab Care. 2010 Nov;13(6):685-9.
46Gong M, Dong H, Tang Y, Huang W, Lu F. Effects of aromatherapy on anxiety: A meta-analysis of randomized controlled trials. J Affect Disord. 2020 Sep 1;274:1028-40.
47Li D, Li Y, Bai X, Wang M, Yan J, Cao Y. The Effects of Aromatherapy on Anxiety and Depression in People With Cancer: A Systematic Review and Meta-Analysis. Front Public Health. 2022 May 30;10:853056.
48Carpenter JK, Andrews LA, Witcraft SM, Powers MB, Smits JAJ, Hofmann SG. Cognitive behavioral therapy for anxiety and related disorders: A meta-analysis of randomized placebo-controlled trials. Depress Anxiety. 2018 Jun;35(6):502-14.
49van Dis EAM, van Veen SC, Hagenaars MA, Batelaan NM, Bockting CLH, van den Heuvel RM, et al. Long-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2020 Mar 1;77(3):265-73.
50Kyriakoulis P, Kyrios M, Nardi AE, Freire RC, Schier M. The Implications of the Diving Response in Reducing Panic Symptoms. Front Psychiatry. 2021 Nov 29;12:784884.
51Faid T, Van Gordon W, Taylor EC. Breathing Exercises, Cold-Water Immersion, and Meditation: Mind-Body Practices Lead to Reduced Stress and Enhanced Well-Being. Adv Mind Body Med. 2022 Summer;36(3):12-20.
52Magnon V, Dutheil F, Vallet GT. Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults. Sci Rep. 2021 Sep 29;11(1):19267.
53Bach D, Groesbeck G, Stapleton P, Sims R, Blickheuser K, Church D. Clinical EFT (Emotional Freedom Techniques) Improves Multiple Physiological Markers of Health. J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X18823691.
54Clond M. Emotional Freedom Techniques for Anxiety: A Systematic Review With Meta-analysis. J Nerv Ment Dis. 2016 May;204(5):388-95.
55Aylett E, Small N, Bower P. Exercise in the treatment of clinical anxiety in general practice - a systematic review and meta-analysis. BMC Health Serv Res. 2018 Jul 16;18(1):559.
56Kandola A, Stubbs B. Exercise and Anxiety. Adv Exp Med Biol. 2020;1228:345-52.
57Smyth JM, Johnson JA, Auer BJ, Lehman E, Talamo G, Sciamanna CN. Online Positive Affect Journaling in the Improvement of Mental Distress and Well-Being in General Medical Patients With Elevated Anxiety Symptoms: A Preliminary Randomized Controlled Trial. JMIR Ment Health. 2018 Dec 10;5(4):e11290.
58Sohal M, Singh P, Dhillon BS, Gill HS. Efficacy of journaling in the management of mental illness: a systematic review and meta-analysis. Fam Med Community Health. 2022 Mar;10(1):e001154.
59Burgstahler MS, Stenson MC. Effects of guided mindfulness meditation on anxiety and stress in a pre-healthcare college student population: a pilot study. J Am Coll Health. 2020 Aug-Sep;68(6):666-72.
60Hoge EA, Bui E, Marques L, Metcalf CA, Morris LK, Robinaugh DJ, Worthington JJ, Pollack MH, Simon NM. Randomized controlled trial of mindfulness meditation for generalized anxiety disorder: effects on anxiety and stress reactivity. J Clin Psychiatry. 2013 Aug;74(8):786-92.
61Firth J, Gangwisch JE, Borisini A, Wootton RE, Mayer EA. Food and mood: how do diet and nutrition affect mental wellbeing? BMJ. 2020 Jun 29;369:m2382.
62Kris-Etherton PM, Petersen KS, Hibbeln JR, Hurley D, Kolick V, Peoples Set al. Nutrition and behavioral health disorders: depression and anxiety. Nutr Rev. 2021 Feb 11;79(3):247-60.