1-androsterone
Scientific names: 3beta-hydroxy-5alpha-androst-1-en-17-one
Alternate names: 1-Androsten-3beta-ol-17-one, 1-Androstène-3bêta-ol-17-one, 1-Androstene-3beta-ol-17-one, 1-Androstène-3bêta-ol-17-one, 1-Dehydroepiandrosterone, 1-DHEA, 3-hydroxy-5alpha-androstan-1-en-17-one, 3-hydroxy-5alpha-androst-1-en-17-one, 3-hydroxyandrost-1-en-17-one, 3beta-hydroxy-androst-1-ene-17-one
Actions: General
Background
1-Androsterone is a type of chemical known as a prohormone. It is converted in the body to testosterone and other sex hormones.
Prohormones like 1-androsterone are included in products marketed to athletes and bodybuilders. They are designed to have effects similar to anabolic steroids. But there is little known about these chemicals and they might cause serious side effects.
People use 1-androsterone for athletic performance and other conditions, but there is no good scientific evidence to support these uses. Using 1-androsterone might also be unsafe.
Don't confuse 1-androsterone with androstenediol, androstenedione, 4-androsterone, androsterone, epiandrosterone and 19-nor-DHEA. These are not the same. 1-Androsterone is banned by the World Anti-Doping Agency (WADA).
Prohormones like 1-androsterone are included in products marketed to athletes and bodybuilders. They are designed to have effects similar to anabolic steroids. But there is little known about these chemicals and they might cause serious side effects.
People use 1-androsterone for athletic performance and other conditions, but there is no good scientific evidence to support these uses. Using 1-androsterone might also be unsafe.
Don't confuse 1-androsterone with androstenediol, androstenedione, 4-androsterone, androsterone, epiandrosterone and 19-nor-DHEA. These are not the same. 1-Androsterone is banned by the World Anti-Doping Agency (WADA).
Safety Safety definitions
When taken by mouth: 1-Androsterone is possibly unsafe. It might cause liver and kidney damage and increase cholesterol.
High cholesterol: 1-Androsterone might worsen cholesterol levels in people who already have high cholesterol.
Kidney disease: 1-Androsterone might damage the kidneys and worsen kidney disease in some people.
Liver problems: 1-Androsterone might damage the liver and worsen liver problems in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: 1-Androsterone is possibly unsafe when taken by mouth during pregnancy or breast-feeding. 1-Androsterone is converted in the body to hormones that might harm pregnancy or a nursing infant. Avoid use.High cholesterol: 1-Androsterone might worsen cholesterol levels in people who already have high cholesterol.
Kidney disease: 1-Androsterone might damage the kidneys and worsen kidney disease in some people.
Liver problems: 1-Androsterone might damage the liver and worsen liver problems in some people.
Effectiveness
Effective Effectiveness definitions
There is interest in using 1-androsterone for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of 1-androsterone might be. 1-Androsterone might also be unsafe. Speak with a healthcare provider before use.
Interactions with pharmaceuticals
Testosterone
Interaction Rating=Moderate Be cautious with this combination.
1-Androsterone is changed by the body to hormones that are closely related to testosterone. Taking 1-androsterone along with other medications that contain testosterone might cause serious side effects such as mood changes and heart, kidney, or liver problems.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 31/01/2024 11:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
