7-keto-dhea
Scientific names: 7-Keto-DHEA
Alternate names: 7-Keto 7-Keto Dehydroepiandrosterone, 7-Keto Déhydroépiandrostérone, 7-oxo-dehydroepiandrosterone, 7-oxo-DHEA, 7-oxoprasterone
Actions: Circulatory, Effects on body weight, Endocrine, Immunologic, Psychiatric
Background
7-keto-DHEA is formed from dehydroepiandrosterone (DHEA) in the body. Unlike DHEA, 7-keto-DHEA is not converted to hormones like androgen and estrogen.
7-keto-DHEA has effects that might promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat.
People take 7-keto-DHEA for obesity, muscle strength, anxiety, depression, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse 7-keto-DHEA with DHEA, 7-alpha-hydroxy-DHEA, 7-beta-hydroxy-DHEA, or raspberry ketone. These are not the same.
7-keto-DHEA has effects that might promote weight loss by speeding up the body's metabolism and converting more energy to heat instead of storing it as fat.
People take 7-keto-DHEA for obesity, muscle strength, anxiety, depression, and many other conditions, but there is no good scientific evidence to support these uses.
Don't confuse 7-keto-DHEA with DHEA, 7-alpha-hydroxy-DHEA, 7-beta-hydroxy-DHEA, or raspberry ketone. These are not the same.
Safety Safety definitions
When taken by mouth: 7-keto-DHEA is possibly safe when used for up to 8 weeks. It seems to be well tolerated when used short-term.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if 7-keto-DHEA is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
Effective Effectiveness definitions
There is interest in using 7-keto-DHEA for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of 7-keto-DHEA might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
It is not known if 7-Keto-DHEA interacts with any medicines. Before taking 7-Keto-DHEA, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 07/12/2023 11:00:00 and last updated on 04/05/2018 01:20:46. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
