American elder
American elder

Background

American elder (Sambucus canadensis) is a plant. Its flower and ripe fruit are used as medicine, but its stem contains toxic chemicals.

American elder flower and ripe fruit are rich sources of vitamin C. But its leaves, stems, and unripe fruit contain chemicals that can cause cyanide poisoning.

People sometimes use American elder for asthma, common cold, sore throat, headache, and many other conditions, but there is no good scientific evidence to support these uses.

Don't confuse American elder with dwarf elder, elderberry, or elderflower. These are not the same.
When taken by mouth: American elder flowers and cooked, ripe fruit are commonly consumed in foods. But there isn't enough reliable information to know if American elder flowers or cooked, ripe fruit are safe when used in larger amounts as medicine. Side effects might include dizziness, nausea, numbness, or vomiting.

American elder leaves, stems, or unripe fruit are possibly unsafe. They contain chemicals that can cause cyanide poisoning. Consuming large amounts of American elder juice can also be unsafe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: American elder leaves, stems, and unripe fruit are likely unsafe when taken by mouth while pregnant or breast-feeding. There isn't enough reliable information to know if the flower or cooked, ripe fruit are safe. Stay on the safe side and avoid use.

Effectiveness

There is interest in using American elder for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of American elder might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

Lithium

Interaction Rating=Moderate Be cautious with this combination.

American elder might have an effect like a water pill or "diuretic." Taking American elder might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver. American elder might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 17/12/2024 11:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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