Antineoplastons
Scientific names: Phenylacetate, Phenylacetylglutamine, Phenylacetylisoglutamine
Alternate names: Antineoplaston A, Antineoplaston A1, Antineoplaston A10, Antineoplaston A10-1, Antineoplaston A2, Antineoplaston A3, Antineoplaston A4, Antineoplaston A5, Antineoplaston AS2-1, Antineoplaston AS2-5, Antineoplaston AS5, Antineoplaston Ch, Antineoplaston F, Antineoplaston H, Antineoplaston K, Antineoplaston L, Antineoplaston O
Actions: Antineoplastic/anti-cancer, Central nervous system (CNS)
Background
Antineoplastons are peptides found in the urine and blood of healthy people. The chemical structures of antineoplastons were determined in the 1980s. Today, most antineoplastons are prepared in a laboratory.
Antineoplastons are used for various cancers, high cholesterol, brain swelling due to infection (encephalitis), HIV/AIDS, Parkinson disease, and other conditions, but there is no good scientific evidence to support these uses.
Antineoplastons are used for various cancers, high cholesterol, brain swelling due to infection (encephalitis), HIV/AIDS, Parkinson disease, and other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when used short-term under the supervision of a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.
When given by IV: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when given short-term by a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE when given in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.
Side effects of antineoplastons include irregular heartbeat, increased blood pressure, skin rash, nausea, vomiting, stomach pain, gas, liver problems, joint swelling, muscle and joint pain, weakness, tiredness, headache, ringing in the ears, dizziness, and fever.
When given by IV: Antineoplastons A10 and AS2-1 are POSSIBLY SAFE in appropriate amounts when given short-term by a healthcare professional. Antineoplastons A10 and AS2-1 are POSSIBLY UNSAFE when given in higher doses or for longer periods of time. Giving antineoplastons in higher doses or for longer periods of time seems to increase the number of side effects. There isn't enough reliable information to know if other types of antineoplastons are safe.
Side effects of antineoplastons include irregular heartbeat, increased blood pressure, skin rash, nausea, vomiting, stomach pain, gas, liver problems, joint swelling, muscle and joint pain, weakness, tiredness, headache, ringing in the ears, dizziness, and fever.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if it is safe to use antineoplastons when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Insufficient evidence Effectiveness definitions
- Brain tumor. Early research shows that using antineoplastons along with standard medications after radiation and surgery might help reduce the size of brain tumors in some people. Other early research shows that injecting antineoplastons intravenously (by IV) might help reduce the size of a specific type of brain tumor, called a glioma, in some adults and children. But other research shows that antineoplastons don't reduce tumor size in people with gliomas. All of the research to date is low-quality.
- Colon cancer. Early research shows that injecting antineoplastons intravenously (by IV) and then taking them by mouth might help people with colon cancer to live longer after having a part of their liver removed.
- A rare tumor that affects the central nervous system (primitive neuroectodermal tumor or PNET). Injecting antineoplastons intravenously (by IV) might help reduce the size of PNETs or keep PNETs from becoming larger in some children with PNET. However, the research to date is low-quality.
- Prostate cancer. Injecting antineoplastons along with the drug diethylstilbestrol might increase the chance of remission in people with prostate cancer. However, the research to date is low-quality.
- Breast cancer.
- Liver cancer.
- Lung cancer.
- High cholesterol.
- Brain swelling due to infection (encephalitis).
- HIV/AIDS.
- Parkinson disease.
- Sickle cell anemia.
- An inherited blood disorder called thalassemia.
- Other conditions.
Dosing & administration
The appropriate dose of antineoplastons depends on several factors such as the user's age, health, and several other conditions. At this time, there is not enough scientific information to determine an appropriate range of doses for antineoplastons. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Interactions with pharmaceuticals
It is not known if this product interacts with any medicines.
Before taking this product, talk with your health professional if you take any medications.
Before taking this product, talk with your health professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Action
Antineoplastons might stimulate the immune system. These peptides might also kill certain cancer cells or prevent them from growing.
vital.ly has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 29/06/2023 10:00:00 and last updated on 23/09/2015 19:31:43. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.
Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
