Apple polyphenols
Alternate names: Apple Phenolics, Apple Polyphenol Extract, Phloretin, Phlorizin
Actions: General, Antiallergic, Antidiabetic, Cardiovascular, Metabolic, Uric acid
Background
Apple polyphenols are chemicals found in apples.
Apple polyphenols are used for obesity, hay fever, high levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia), and many other conditions, but there is no good scientific evidence to support these uses.
Apple polyphenols are used for obesity, hay fever, high levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia), and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Apple polyphenols are POSSIBLY SAFE when taken short-term. Taking apple polyphenols might cause mild gastrointestinal side effects, such as diarrhea.
When applied to the skin: Apple polyphenols are POSSIBLY SAFE when used appropriately.
When applied to the skin: Apple polyphenols are POSSIBLY SAFE when used appropriately.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if apple polyphenols are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Insufficient evidence Effectiveness definitions
- Male-pattern baldness (androgenic alopecia). Early research shows that applying an apple polyphenol product to the scalp can increase hair growth in some men with male-pattern baldness.
- Hay fever. Early research shows that drinking a drink with apple polyphenols reduces runny nose in people with hay fever. Other early research shows that taking apple polyphenol once daily for 12 weeks, starting about 2 weeks before cedar pollen season, can reduce sneezing in patients with a specific form of hay fever called Japanese cedar pollinosis.
- Athletic performance. Early research shows that taking apple and grape polyphenols can allow athletes to exercise for a little bit longer before getting tired.
- High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Early research shows that eating apples with more polyphenols does not affect cholesterol levels compared to eating apples with low polyphenols. But not all research agrees.
- High blood pressure. Early research shows that taking apple polyphenols does not seem to improve blood pressure in people with high blood pressure.
- Obesity. Early research shows that drinking a beverage with apple polyphenols can reduce the amount of body fat in adults who are overweight or obese.
Dosing & administration
The appropriate dose of apple polyphenols depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for apple polyphenols. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Interactions with pharmaceuticals
Insulin
Interaction Rating=Moderate Be cautious with this combination.
Taking apple polyphenols before a meal might cause blood glucose levels to rise more slowly after a meal. Using insulin before a meal also lowers blood glucose levels after a meal. Taking apple polyphenol extract along with insulin might cause your blood sugar to go too low. Monitor your blood sugar closely. The timing of your insulin dose might need to be changed.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Action
Apple polyphenols are antioxidants. Apple polyphenols also seem to block fat and cholesterol from entering the body and slow the production of fat and cholesterol. This may allow them to lower cholesterol and help with weight loss.
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This monograph was last reviewed on 12/09/2024 10:00:00 and last updated on 02/12/2020 23:17:54. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
