Cetylated fatty acids (cfas)
Cetylated fatty acids (cfas)

Background

Cetylated fatty acids are fatty acids mixed with cetyl alcohol in a lab. The most common is cetyl myristoleate. Natural cetylated fatty acids are rare.

Cetylated fatty acids might help lubricate joints and muscles, soften tissues, and increase flexibility. They also might help the immune system and reduce swelling.

People commonly use cetylated fatty acids for osteoarthritis. They are also used for other types of arthritis, knee pain, fibromyalgia, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: Cetylated fatty acids are possibly safe. The European Food Safety Authority considers cetylated fatty acids to be safe when used in doses up to 1.6 grams daily. It's not clear what the side effects might be.

When applied to the skin: Cetylated fatty acids are possibly safe when used for up to 30 days. Some people might be sensitive to creams containing cetylated fatty acids, but they're usually well-tolerated.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if cetylated fatty acids are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Osteoarthritis. Taking a specific blend of cetylated fatty acids combined with soy lecithin and fish oil seems to decrease pain and improve knee motion in people with knee osteoarthritis. Also, applying cetylated fatty acids directly to the skin may decrease pain and improve function in people with this condition.
There is interest in using cetylated fatty acids for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of cetylated fatty acids might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if Cetylated Fatty Acids (CFAs) interacts with any medicines. Before taking Cetylated Fatty Acids (CFAs), talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
vital.ly has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 12/04/2024 10:00:00 and last updated on 01/12/2020 00:54:18. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.