D-mannose
D-mannose

Background

D-mannose is a kind of sugar that is related to glucose. It's found in many fruits, and also occurs naturally in the human body.

D-mannose might help treat a deficiency caused by a genetic defect. D-mannose might also prevent certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection.

D-mannose is used for an inherited disorder called carbohydrate-deficient glycoprotein syndrome type 1b. It is also used for UTIs, but there is no good scientific evidence to support this use.
When taken by mouth: D-mannose is possibly safe for most adults when taken for up to 6 months. It can cause diarrhea and nausea. There isn't enough reliable information to know if d-mannose is safe or what the side effects might be when taken for more than 6 months.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if d-mannose is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: D-mannose is possibly safe when taken by mouth in children with an inherited disorder called carbohydrate-deficient glycoprotein syndrome type 1b. It can cause diarrhea, loose stools, bloating, and nausea in these children. There isn't enough reliable information to know if d-mannose is safe to use in children who do not have this condition.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
  • An inherited disorder called carbohydrate-deficient glycoprotein syndrome type 1b. Taking d-mannose by mouth can improve digestive problems, low blood sugar, and blood clotting disorders in people with this condition. It's not clear if it helps prevent liver problems.
There is interest in using d-mannose for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of d-mannose might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

It is not known if D-Mannose interacts with any medicines. Before taking D-Mannose, talk with your healthcare professional if you take any medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
D-Mannose Powder
0.0 ()
4.6 (7)
Practitioner product
vital.ly has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 01/05/2024 10:00:00 and last updated on 29/12/2020 23:17:47. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.