Deanol
Scientific names: 2-Dimethylaminoethanol
Alternate names: 2-Dimethyl Aminoethanol, Acéglumate de Déanol, Acétamido-benzoate de Déanol, Benzilate de Déanol, Bisorcate de Déanol, Cyclohexylpropionate de Déanol, Deaner, Déanol, Deanol Aceglumate, Deanol Acetamidobenzoate, Deanol Benzilate, Deanol Bisorcate, Deanol Cyclohexylpropionate, Deanol Hemisuccinate, Deanol Pidolate, Deanol Tartrate, Dimethylaminoethanol, Diméthylaminoéthanol, Dimethylaminoethanol Bitartrate, Dimethylethanolamine, DMAE, DMAE Bitartrate, Hémisuccinate de Déanol, Pidolate de Déanol
Background
Deanol is a chemical used to make choline. Choline is involved in reactions that form acetylcholine, a chemical in the brain and other areas of the body.
Having more choline in the body might increase the production of acetylcholine, which is involved in brain and nervous system function. This might have effects on some neurological conditions.
People use deanol for Alzheimer disease, a movement disorder called tardive dyskinesia, attention deficit-hyperactivity disorder (ADHD), autism, and many other conditions, but there is no good scientific evidence to support these uses.
Deanol was previously sold by Riker Laboratories as the prescription drug Deaner. It was prescribed for the management of children with behavior problems and learning difficulties. Deanol is not an approved food additive in the US, nor is it an orphan drug, as some marketing suggests.
Having more choline in the body might increase the production of acetylcholine, which is involved in brain and nervous system function. This might have effects on some neurological conditions.
People use deanol for Alzheimer disease, a movement disorder called tardive dyskinesia, attention deficit-hyperactivity disorder (ADHD), autism, and many other conditions, but there is no good scientific evidence to support these uses.
Deanol was previously sold by Riker Laboratories as the prescription drug Deaner. It was prescribed for the management of children with behavior problems and learning difficulties. Deanol is not an approved food additive in the US, nor is it an orphan drug, as some marketing suggests.
Safety Safety definitions
When taken by mouth: Deanol is possibly safe when used in doses up to 2 grams daily for up to 4 weeks or 500 mg daily for up to 3 months. It seems to be well tolerated. Side effects might include stomach cramps, stomach pain, diarrhea, drowsiness, nausea, and vomiting.
When applied to the skin: There isn't enough reliable information to know if deanol is safe or what the side effects might be.
Depression: Deanol might make depression worse.
Schizophrenia: Deanol might make schizophrenia symptoms worse.
Tonic-clonic seizures: Deanol should not be used by people with tonic-clonic seizure disorders. It might make seizures worse.
When applied to the skin: There isn't enough reliable information to know if deanol is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if deanol is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Depression: Deanol might make depression worse.
Schizophrenia: Deanol might make schizophrenia symptoms worse.
Tonic-clonic seizures: Deanol should not be used by people with tonic-clonic seizure disorders. It might make seizures worse.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely ineffective Effectiveness definitions
- Alzheimer disease. Taking deanol by mouth does not seem to improve memory in people with Alzheimer disease.
- A movement disorder often caused by antipsychotic drugs (tardive dyskinesia). Taking deanol by mouth does not seem to improve symptoms of tardive dyskinesia.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of deanol might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
Drying medications (Anticholinergic drugs)
Interaction Rating=Minor Be watchful with this combination.
Deanol can increase a chemical in the body called acetylcholine. Acetylcholine plays a big part in many important body functions. Some medications, called anticholinergic drugs, block the effects of acetylcholine in the body. Taking deanol might decrease the effects of anticholinergic drugs.
Various medications used for glaucoma, Alzheimer disease, and other conditions (Cholinergic drugs)
Interaction Rating=Minor Be watchful with this combination.
Deanol can increase a chemical in the body called acetylcholine. Some medications that are used for glaucoma, Alzheimer disease, and other conditions, also increase acetylcholine levels. Taking deanol with these medications might increase the chance of side effects.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 31/07/2024 10:00:00 and last updated on 03/09/2020 02:40:19. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
