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Dimethylhexylamine (dmha)
Scientific names: 6-methylheptan-2-amine
Alternate names: 2-Amino-5-Methylheptane, 2-Amino-5-Méthylheptane, 2-Amino-6-Methylheptane, 2-Amino-6-Methylheptane, 2-Amino-6-Méthylheptane, 2-Aminoisoheptane, 2-Heptylamine, 6-Methyl-2-Heptylamine, 6-Méthyl-2-Heptylamine, 6-Methyl-2-Isooctyl Amine, 6-Méthylheptane-2-Amine, Aconite Extract, Aconitum Kusnezoffii, Amino-5-Methylheptane, Amidrine, Extrait d’Aconit, Octodrina, Octodrine, Vaporpac
Actions: Analgesic, Anesthetic, Antibacterial activity, Antifungal activity, Cardiovascular, Stimulant
Background
Dimethylhexylamine (DMHA) is a stimulant similar to dimethylamylamine (DMAA), which is banned by many sports and governments due to safety concerns.
DMHA is structurally similar to DMAA. Some products claim that DMHA comes naturally from aconite plants, but there is no clear evidence that DMHA can be found in these plants. DMHA found in dietary supplements is likely made in a lab rather than produced from natural sources.
People use DMHA for athletic performance, obesity, and other conditions, but there is no good scientific evidence to support these uses.
Don't confuse DMHA with aconite, 1,3-DMAA, 1,4-DMAA, or Ostarine. These are not the same.
DMHA is structurally similar to DMAA. Some products claim that DMHA comes naturally from aconite plants, but there is no clear evidence that DMHA can be found in these plants. DMHA found in dietary supplements is likely made in a lab rather than produced from natural sources.
People use DMHA for athletic performance, obesity, and other conditions, but there is no good scientific evidence to support these uses.
Don't confuse DMHA with aconite, 1,3-DMAA, 1,4-DMAA, or Ostarine. These are not the same.
Safety Safety definitions
When taken by mouth: DMHA is possibly unsafe. DMHA might cause side effects similar to dimethylamylamine (DMAA), including heart attack and death.
High blood pressure: DMHA might have stimulant effects and increase blood pressure. Avoid use.
Glaucoma: DMHA might have stimulant effects and cause blood vessels to constrict. This could worsen some types of glaucoma.
Surgery: DMHA might have stimulant effects. This might interfere with surgery by increasing heart rate and blood pressure. Stop taking DMHA at least 2 weeks before a scheduled surgery.
Irregular heartbeat (heart arrhythmia): DMHA might have stimulant effects and cause a rapid heartbeat. This could worsen heart arrhythmias. If you have an irregular heartbeat, avoid taking DMHA.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if DMHA is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.High blood pressure: DMHA might have stimulant effects and increase blood pressure. Avoid use.
Glaucoma: DMHA might have stimulant effects and cause blood vessels to constrict. This could worsen some types of glaucoma.
Surgery: DMHA might have stimulant effects. This might interfere with surgery by increasing heart rate and blood pressure. Stop taking DMHA at least 2 weeks before a scheduled surgery.
Irregular heartbeat (heart arrhythmia): DMHA might have stimulant effects and cause a rapid heartbeat. This could worsen heart arrhythmias. If you have an irregular heartbeat, avoid taking DMHA.
Effectiveness
Effective Effectiveness definitions
There is interest in using DMHA for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of DMHA might be. DMHA might also be unsafe. Speak with a healthcare provider before use.
Interactions with pharmaceuticals
Stimulant drugs
Interaction Rating=Moderate Be cautious with this combination.
Stimulants, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. DMHA might also speed up the nervous system. Taking DMHA along with stimulant drugs might cause serious problems, including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with DMHA .
Interactions with herbs & supplements
Herbs and supplements with stimulant properties: DMHA might have stimulant effects. Taking it with other supplements with similar effects might increase the chance of side effects, including rapid heartbeat and high blood pressure. Examples of supplements with this effect include 1,3-DMAA, bitter orange, caffeine-containing products, and ephedra.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 31/01/2024 11:00:00 and last updated on 06/08/2020 01:56:37. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
