Fermented wheat germ extract
Alternate names: Extrait Fermenté de Germe de Blé, Extrait de Germe de Blé Fermenté, Extrait de Germe Triticum Vulgare, Fermented Extract Of Wheat Germ, FWGE, Germe de Blé Triticum Aestivum, MSC, Triticum Aestivum Germ Extract, Triticum Vulgare Germ Extract
Actions: Anticancer, Antioxidant, Immunomodulating
Background
Fermented wheat germ extract is made by fermenting extract of wheat germ with yeast. Wheat germ is the nutrient-rich embryo of the wheat kernel.
Fermented wheat germ extract contains chemicals that are thought to help treat cancer. It also has antioxidant effects.
People use fermented wheat germ extract for colon and rectal cancer, skin cancer, prostate cancer, rheumatoid arthritis (RA), and many other conditions, but there is no good scientific evidence to support these uses.
Fermented wheat germ extract contains chemicals that are thought to help treat cancer. It also has antioxidant effects.
People use fermented wheat germ extract for colon and rectal cancer, skin cancer, prostate cancer, rheumatoid arthritis (RA), and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Fermented wheat germ extract is possibly safe. A specific wheat germ extract (Avemar) has been used safely in doses of 8.5-9 grams once or twice daily for up to 1 year. It's usually well-tolerated. Side effects might include diarrhea or nausea.
When applied to the skin: There isn't enough reliable information to know if fermented wheat germ extract is safe or what the side effects might be.
Children: Fermented wheat germ extract is possibly safe when taken by mouth. A specific wheat germ extract (Avemar) has been used safely for about 29 months.
Organ transplant recipients: Fermented wheat germ extract might increase the immune system. This might increase the risk of organ transplant rejection. If you have received an organ transplant, don't use fermented wheat germ extract until more is known.
When applied to the skin: There isn't enough reliable information to know if fermented wheat germ extract is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if fermented wheat germ extract is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Fermented wheat germ extract is possibly safe when taken by mouth. A specific wheat germ extract (Avemar) has been used safely for about 29 months.
Organ transplant recipients: Fermented wheat germ extract might increase the immune system. This might increase the risk of organ transplant rejection. If you have received an organ transplant, don't use fermented wheat germ extract until more is known.
Effectiveness
Effective Effectiveness definitions
There is interest in using fermented wheat germ extract for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
A specific wheat germ extract (Avemar) has most often been used by adults in doses of 8.5-9 grams by mouth once or twice daily for up to 1 year. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Fermented wheat germ extract can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking fermented wheat germ extract along with these medications might decrease the effects of these medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 22/02/2023 11:00:00 and last updated on 10/07/2020 00:19:41. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
