Gamma-oryzanol
Scientific names: Gamma-oryzanol
Alternate names: Gama Orizanol, Gamma Oryzanol, Gamma-OZ, Oryzanol
Actions: Antidiabetic, Anti-inflammatory, Antioxidant, Antitumor, Antiulcerative, Carcinogenic, Central nervous system, Coagulation, Cytochrome P450, Endocrine, Gastric secretion, Gastrointestinal, Hypocholesterolemic, Immunostimulant, Insulin sensitivity, Mutagenic
Background
Gamma-oryzanol is group of chemicals found in rice bran oil. It is also found in wheat bran and some fruits and vegetables.
Gamma-oryzanol isn't absorbed well in the gut. Because of this, it might reduce cholesterol levels by reducing how much cholesterol is absorbed from foods.
People use gamma-oryzanol for high cholesterol, symptoms of menopause, athletic performance, eczema, high blood pressure, and many other conditions, but there is no good scientific evidence to support most of these uses.
Gamma-oryzanol isn't absorbed well in the gut. Because of this, it might reduce cholesterol levels by reducing how much cholesterol is absorbed from foods.
People use gamma-oryzanol for high cholesterol, symptoms of menopause, athletic performance, eczema, high blood pressure, and many other conditions, but there is no good scientific evidence to support most of these uses.
Safety Safety definitions
When taken by mouth: Gamma-oryzanol is possibly safe when used in doses up to 300 mg daily. It seems to be well-tolerated.
When applied to the skin: Gamma-oryzanol is possibly safe when used appropriately.
Thyroid conditions: Gamma-oryzanol might change thyroid function. Speak with a healthcare provider before using gamma-oryzanol if you have a thyroid condition.
When applied to the skin: Gamma-oryzanol is possibly safe when used appropriately.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if gamma-oryzanol is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Thyroid conditions: Gamma-oryzanol might change thyroid function. Speak with a healthcare provider before using gamma-oryzanol if you have a thyroid condition.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Abnormal levels of cholesterol or blood fats (dyslipidemia). Taking gamma-oryzanol by mouth might decrease total cholesterol, low-density lipoprotein (LDL or "bad") cholesterol, and blood fats called triglycerides in people with high cholesterol.
Dosing & administration
Gamma-oryzanol has most often been used by adults in doses of 100-300 mg by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
It is not known if Gamma-oryzanol interacts with any medicines. Before taking Gamma-oryzanol, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
vital.ly has licensed monographs from TRC Healthcare.
This monograph was last reviewed on 31/05/2023 10:00:00 and last updated on 08/12/2020 03:04:31. Monographs are reviewed and/or updated multiple times per month and at least once per year.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. No reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. It is unlawful to download, store, or distribute content from this site.
Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
