Background

Gotu kola (Centella asiatica) is an herb in the parsley family. It has a long history of use in the traditional Chinese and Ayurvedic medicine systems.

Gotu kola contains certain chemicals that seem to decrease swelling and blood pressure. It also seems to increase collagen production, which might be helpful for wound healing.

People use gotu kola for burns and poor circulation that can lead to varicose veins. It is also used for scars, stretch marks, and many other conditions, but there is no good scientific evidence to support most of these uses.

Safety Safety definitions

When taken by mouth: Gotu kola extract is possibly safe for most people when taken for up to 12 months. It might cause nausea and stomach pain.

When applied to the skin: Gotu kola is possibly safe when used for up to 10 weeks. It might cause itchiness and redness.

Special Precautions & Warnings:

Pregnancy: Gotu kola is possibly safe when applied to the skin during pregnancy. There isn't enough reliable information to know if gotu kola is safe to take by mouth when pregnant. Stay on the safe side and avoid use.

Breast-feeding: There isn't enough reliable information to know if gotu kola is safe to use when breast-feeding. Stay on the safe side and avoid use.

Liver disease: Gotu kola might cause liver damage. People who already have a liver disease should avoid using gotu kola. It might make liver problems worse.

Surgery: Gotu kola might cause too much sleepiness if combined with medications used during and after surgery. Stop using gotu kola at least 2 weeks before a scheduled surgery.

Effectiveness

Dosing & administration

Gotu kola extract has most often been used by adults in doses of 60-450 mg by mouth daily for 4-12 months. It's also used in creams, gels, and ointments. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

Interactions with pharmaceuticals

Medications that can harm the liver (Hepatotoxic drugs)

Interaction Rating=Moderate Be cautious with this combination.

Gotu kola might harm the liver. Some medications can also harm the liver. Taking gotu kola along with a medication that can harm the liver might increase the risk of liver damage.

Sedative medications (CNS depressants)

Interaction Rating=Moderate Be cautious with this combination.

Gotu kola might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking gotu kola with sedative medications might cause breathing problems and/or too much sleepiness.

Interactions with herbs & supplements

Herbs and supplements that might harm the liver: Gotu kola might harm the liver. Taking it with other supplements that can also harm the liver might increase the risk of liver damage. Examples of supplements with this effect include garcinia, greater celandine, green tea extract, kava, and kratom.
Herbs and supplements with sedative properties: Gotu kola might cause sleepiness and slowed breathing. Taking it along with other supplements with similar effects might cause too much sleepiness and/or slowed breathing in some people. Examples of supplements with this effect include hops, kava, L-tryptophan, melatonin, and valerian.

Interactions with foods

There are no known interactions with foods.