Kaolin
Kaolin

Background

Kaolin is a type of clay found in nature. It is sometimes used to make medicine. It is also used as a filler in tablets.

Kaolin is used to stop bleeding and for a condition that involves swelling and sores in the mouth (oral mucositis). It is also used for diarrhea and many other conditions, but there is no good scientific evidence to support most of these uses.
When taken by mouth: Kaolin is LIKELY SAFE for most people when taken in foods amounts. It is POSSIBLY SAFE when used as kaolin-pectin in medicines and mouthwashes. It can cause some side effects including constipation. Kaolin is POSSIBLY UNSAFE when used in very large amounts on a daily basis. It can cause blockage of the intestines and low blood iron levels.

When applied to the skin: Kaolin is LIKELY SAFE when used in FDA-approved wound dressings.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Kaolin is LIKELY SAFE when taken by mouth in food amounts. Kaolin is POSSIBLY SAFE when used as kaolin-pectin in medicines.

Effectiveness

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
  • Swelling (inflammation) and sores inside the mouth (oral mucositis). Using kaolin in a mouth rinse seems to decrease the pain of mouth sores caused by radiation treatment.
  • Bleeding. Pressing on an artery using a kaolin pad seems to stop bleeding faster than pressing with a regular pad. Also, applying a pad containing kaolin to a surgical wound seems to stop bleeding faster than applying a regular pad.
There is interest in using kaolin for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

The following doses have been studied in scientific research:

ADULT

BY MOUTH:
  • For swelling (inflammation) and sores inside the mouth (oral mucositis): A mouth rinse containing 15 mL of a mixture of kaolin-pectin and diphenhydramine syrup has been used four times a day.
APPLIED TO THE SKIN:
  • For bleeding: A pad containing kaolin has been applied with pressure to wounds to stop bleeding.
CHILDREN

APPLIED TO THE SKIN:
  • For bleeding: A pad containing kaolin has been applied to wounds after surgery to stop bleeding.

Interactions with pharmaceuticals

Clindamycin (Cleocin)

Interaction Rating=Moderate Be cautious with this combination.

Kaolin might decrease how quickly the body absorbs clindamycin (Cleocin), an antibiotic. But it probably doesn't decrease the amount of clindamycin (Cleocin) that is absorbed.

Digoxin (Lanoxin)

Interaction Rating=Moderate Be cautious with this combination.

Kaolin might decrease the absorption and decrease the effectiveness of digoxin (Lanoxin), a heart medication. To avoid a potential interaction, separate digoxin (Lanoxin) and kaolin doses by at least three hours.

Quinidine

Interaction Rating=Moderate Be cautious with this combination.

Kaolin might decrease the absorption and decrease the effectiveness of quinidine (Quinidex), a heart medication. To avoid a potential interaction, separate quinidine (Quinidex) and kaolin doses by at least three hours.

Trimethoprim (Proloprim)

Interaction Rating=Moderate Be cautious with this combination.

Kaolin might decrease the absorption and decrease the effectiveness of trimethoprim (Proloprim), an antibiotic. To avoid a potential interaction, separate trimethoprim (Proloprim) and kaolin doses by at least three hours.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.

Action

When held in the mouth, a mouthwash containing kaolin produces a protective coating for mouth sores.

When kaolin is applied to wounds it speeds up blood clotting.
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This monograph was last reviewed on 29/12/2022 18:06:15 and last updated on 01/12/2021 07:48:22. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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