Lipase
Scientific names: Lipase
Alternate names: Bile Salt-Dependent Lipase, Bile Salt-Stimulated Lipase, Carboxyl Ester Lipase, Lipasa, Recombinant Bile Salt-Dependent Lipase, Triacylglycerol Lipase, Triglyceride Lipase
Background
Lipase is an enzyme that breaks down fats during digestion. It is found in many plants, animals, bacteria, and molds. Some people use lipase as a medicine.
Since lipase breaks down fat into smaller pieces, it is possible that lipase supplements might make digestion easier.
Lipase is used for indigestion (dyspepsia), heartburn, and other gastrointestinal problems, but there is no good scientific evidence to support these uses.
Do not confuse lipase with pancreatic enzyme products. Pancreatic enzyme products contain multiple ingredients, including lipase. Some of these products are approved by the US FDA for digestion problems due to a disorder of the pancreas (pancreatic insufficiency).
Since lipase breaks down fat into smaller pieces, it is possible that lipase supplements might make digestion easier.
Lipase is used for indigestion (dyspepsia), heartburn, and other gastrointestinal problems, but there is no good scientific evidence to support these uses.
Do not confuse lipase with pancreatic enzyme products. Pancreatic enzyme products contain multiple ingredients, including lipase. Some of these products are approved by the US FDA for digestion problems due to a disorder of the pancreas (pancreatic insufficiency).
Safety Safety definitions
When taken by mouth: There isn't enough reliable information to know if lipase is safe or what the side effects might be.
Children: There isn't enough reliable information to know if lipase is safe for full-term infants or older children. But in premature infants, a specific form of lipase, called bile salt-stimulated lipase, is possibly unsafe. Adding this type of lipase to formula can increase the risk of side effects in the gut.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if lipase is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: There isn't enough reliable information to know if lipase is safe for full-term infants or older children. But in premature infants, a specific form of lipase, called bile salt-stimulated lipase, is possibly unsafe. Adding this type of lipase to formula can increase the risk of side effects in the gut.
Effectiveness
Effective Effectiveness definitions
There is interest in using lipase for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of lipase might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
It is not known if Lipase interacts with any medicines. Before taking Lipase, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per capsule:
- Rhizopus oryzae (Microfungus) 9.4 mg equiv. lipase 525 LipU
- Ananas comosus (Bromelain) 217800 PU
- Carica papaya (Papain) 235200 PU
- Aspergillus oryzae (Kōji mould) 5.7 mg equiv. amylase 750 DUAA
- Aspergillus oryzae (Kōji mould) 4.75 mg equiv. protease 3709 HUT
- Lactobacillus acidophilus (MED 27 & MED 28) 5 billion CFU
- Lactobacillus rhamnosus (MED 26) 2.5 billion CFU
- Bifidobacterium bifidum (MED 11) 125 million CFU
- Bifidobacterium animalis ssp. lactis (MED 13) 1.125 billion CFU
Practitioner product
Per capsule:
- Rhizopus oryzae (Microfungus) 4.6 mg equiv. lipase 500 LipU
- Aspergillus oryzae 190 mg equiv. protease 60000 HUT
- Trichoderma longibrachiatum (Trichoderma fungus) 5.5 mg equiv. cellulase 1000 CU
- Punica granatum ext. 62.5 mg
- Cinnamomum verum ext. 50 mg
Practitioner product
Practitioner product
Per capsule:
- Lipase 2000 LipU
- Protease 70000 HUT
- Amylase enzyme 23000 DU
- Cellulase 1000 CU
- Beta-D-galactosidase (Tilactase) 900 ALU
Practitioner product
Practitioner product
Per capsule:
- Lipase 1200 LipU
- Iberis amara ext. 50 mg
- Lactobacillus brevis 1 billion CFU
- Lactobacillus fermentum 1 billion CFU
- Lactobacillus helveticus 1 billion CFU
- Lactobacillus bulgaricus 2 billion CFU
- Lactobacillus paracasei 1 billion CFU
- Lactobacillus reuteri 1 billion CFU
- Lactobacillus rhamnosus 1 billion CFU
- Lactobacillus salivarius 1 billion CFU
- Streptococcus thermophilus 1 billion CFU
- Allium sativum powder 100 mg
- Wolfiporia extensa ext. 125 mg
- Arthrospira platensis (Spirulina) 50 mg
Practitioner product
Practitioner product
Per 5 g (Cucumber Lime):
- Lipase 750 LipU
- Brassica oleracea var. italica powder 250 mg
- Arthrospira platensis (Spirulina) 100 mg
- Cordyceps sinensis 105 mg
- Lentinula edodes 100 mg
- Trametes versicolor 70 mg
- Astragalus membranaceus 100 mg
- Camellia sinensis 500 mg
- Grifola frondosa 125 mg
- Spinacia oleracea (Spinach) 175 mg
- Brassica oleracea var. acephala (leaf) powder (Kale) 175 mg
- Nasturtium officinale 160 mg
- Apium graveolens powder 110 mg
- Pleurotus eryngii 100 mg
- Protease 1000 DU
- Ananas comosus (Bromelain) 350 GDU
- Carica papaya (Papain) 40 mg
- L-glutamine 500 mg
- Bacillus coagulans 4 billion CFU
- Lactobacillus rhamnosus 750 million CFU
- Saccharomyces cerevisiae (boulardii) (SB) 500 million CFU
- Quercetin 100 mg
- Taraxacum officinale 100 mg
- Coriandrum sativum 80 mg
- Zingiber officinale 50 mg
- Rosmarinus officinalis 50 mg
- Origanum vulgare powder 50 mg
- Natural flavours
- Stevia rebaubiana ext.
- Eleutherococcus senticosus 100 mg
- Citric acid anhydrous
- Chlorella vulgaris powder 175 mg
150 g Cucumber Lime
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Per capsule:
- Lipase 600 LipU
- L-glutamic acid 25 mg
- Glutamic acid hydrochloride 25 mg
- Echinacea angustifolia ext. 25 mg
- Saccharomyces cerevisiae (SB) 35.72 mg equiv. bakers yeast beta glucan 178.6 mg
- Cichorium intybus powder 33.19 mg
- Bifidobacterium animalis ssp. lactis 0.5 billion CFU
- Bifidobacterium bifidum 0.5 billion CFU
- Bifidobacterium infantis 0.5 billion CFU
- Lactobacillus acidophilus 0.5 billion CFU
- Lactobacillus brevis 0.25 billion CFU
- Lactobacillus casei 0.25 billion CFU
- Lactobacillus delbrueckii ssp. bulgaricus 0.25 billion CFU
- Lactobacillus fermentum 0.25 billion CFU
- Lactobacillus gasseri 0.25 billion CFU
- Lactobacillus helveticus 0.25 billion CFU
- Lactobacillus paracasei 0.5 billion CFU
- Lactobacillus plantarum 0.25 billion CFU
- Lactobacillus reuteri 0.25 billion CFU
- Lactobacillus rhamnosus 0.25 billion CFU
- Lactobacillus salivarius 0.25 billion CFU
- Polyporus umbellatus powder 50 mg
- Grifola frondosa powder 50 mg
- Cordyceps sinensis powder 50 mg
- Ganoderma lucidum powder 25 mg
- Poria cocos ext. 25 mg
- Arthrospira platensis (Spirulina) 55 mg
- Yeast 25 mg equiv. selenium 50 µg
- Iberis amara ext. 50 mg
- Apple pectin 25 mg
- Yucca gloriosa ext. 25 mg
Practitioner product
Per capsule:
Practitioner product
Per capsule:
- Lipase 500 FCC LU
- Amylase enzyme 10000 DU
- Protease 4.5 30000 HUT
- Lactase 1500 ALU
- Glucoamylase 60 AGU
- Cellulase 1000 CU
- Invertase 500 SU
Practitioner product
Per capsule:
- Lipase 500 LipU
- Protease 30000 HUT
- Tilactase 1500 ALU
- Amylase enzyme 12000 DU
- Cellulase 1000 CU
Practitioner product
Per capsule:
- Lipase 400 LipU
- Amylase enzyme 10000 DUAA
- Protease 60000 HUT
- Tilactase 1500 ALU
- Cellulase 125 CU
- Ananas comosus (Bromelain) 1500000 PU
- Gentiana lutea ext. 120 mg
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Per capsule:
- Lipase 250 LipU
- Amylase enzyme 3500 DU
- Cellulase 350 CU
- Beta-D-galactosidase (Tilactase) 2250 ALU
- Protease 24500 HUT
Practitioner product
Per capsule:
- Lipase 100 LipU
- Amylase enzyme 4500 DUAA
- Protease 10800 HUT
- Beta-D-galactosidase (Tilactase) 500 ALU
- Cellulase 80 CU
Practitioner product
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Practitioner product
Per capsule:
- Lipase 40 LipU
- Protease 31250 HUT
- Amylase enzyme 10000 DUAA
- Cellulase 4000 CU
Practitioner product
Per 30 g (Choc Sea Salt):
- Lipase 160 µg
- Pea protein isolate
- Pumpkin powder
- Citrullus lanatus (Watermelon)
- Cannabis sativa (seed) powder
- Schizochytrium sp. (Chromista algae oil)
- d-alpha-Tocopherol
- Medium Chain Triglycerides (powder) (MCT)
- Amylase enzyme 3840 µg
- Protease 960 µg
- Lactase 640 µg
- Cellulase 32 µg
- Flavour
- Pink Himalayan crystal salt
- Theobroma cacao
- Stevia rebaubiana
900 g Choc Sea Salt
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Per 9 g:
- Lipase
- Chlorella pyrenoidosa powder
- Brassica oleracea var. acephala (leaf) powder (Kale)
- Inulin (Dietary fibre)
- Medicago sativa
- Brassica oleracea var. italica (Broccoli)
- Spinacia oleracea (Spinach)
- Green banana
- Bacillus coagulans (GBI-30)
- Arthrospira platensis (Spirulina)
- Laminaria digitara (Kelp)
- Euterpe oleracea (berry) ext. (Acai)
- Vaccinium corymbosum
- Malpighia glabra
- Beta vulgaris
- Punica granatum juice dry
- Lycium chinese
- Golden pea protein (sprout) bio-fermented
- Apple pectin
- Rubus idaeus (berry)
- Fragaria ananassa (Strawberry)
- Hippophae rhamnoides
- Lycopersicon esculentum
- Arctic sea algae
- Sea salt
- Sunflower seed extract
- Ananas comosus (Pineapple)
- Citrus limon (Lemon)
- Linum usitatissimum (seed) (Flaxseed)
- Malus (Apple)
- Lepidium meyenii
- Natural flavours
- Silybum marianum
- Equisetum arvense
- Centella asiatica
- Glycyrrhiza glabra (root)
- Althaea officinalis (root)
- Melissa officinalis
- Taraxacum officinale (leaf)
- Zingiber officinale (root)
- Withania somnifera
- Aloe barbadensis (leaf)
- Panax ginseng
- Pumpkin powder
- Sweet potato powder
- Sunflower seed
- Vaccinium macrocarpon
- Grifola frondosa (mushroom)
- Lentinula edodes (mushroom)
- Myrciaria dubia (fruit) powder (Camu Camu)
- Protease
- Amylase enzyme
- Cellulase
- Lactase
- Mesquite (pod) powder
- Thaumatin
- Prunus salicina (Queen Garnet plum)
- Chlorella pyrenoidosa powder
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
