Lysine
Alternate names: Hydrochlorure de L-Lysine, Lisina, L-Lysine, L-Lysine HCl, L-Lysine Hydrochloride, L-Lysine Monohydrochloride, Lys, Lysine HCl, Lysine Hydrochloride, Lysine Monohydrochloride, Monochlohydrate de L-Lysine, Monochlohydrate de Lysine
Actions: Antiviral, Bone, Lipid, Neurologic
Background
Lysine is an essential amino acid. The human body cannot make lysine, so it must be eaten in the diet. Sources include meat, fish, dairy, and eggs.
Lysine is a building block for making proteins in the body. It might also prevent the herpes virus from growing.
People use lysine for cold sores, canker sores, athletic performance, diabetes, and many other conditions, but there is no good scientific evidence to support most of these uses.
Lysine is a building block for making proteins in the body. It might also prevent the herpes virus from growing.
People use lysine for cold sores, canker sores, athletic performance, diabetes, and many other conditions, but there is no good scientific evidence to support most of these uses.
Safety Safety definitions
When taken by mouth: Lysine is possibly safe for most people when taken in doses up to 3000 mg daily for up to one year. It can cause side effects such as stomach pain and diarrhea.
When applied to the skin: Lysine is possibly safe for most people when used short-term.
Lysinuric protein intolerance: Lysine supplementation might cause diarrhea and stomach cramps in children who have this rare genetic disorder.
When applied to the skin: Lysine is possibly safe for most people when used short-term.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if lysine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Lysinuric protein intolerance: Lysine supplementation might cause diarrhea and stomach cramps in children who have this rare genetic disorder.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Cold sores (herpes labialis). Taking lysine by mouth might help prevent and heal cold sores. It's not clear if applying it to the skin helps.
Dosing & administration
Lysine has most often been used by adults in doses up to 3 grams daily for up to 1 year. It's also available in different topical products such as creams. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
Interactions with pharmaceuticals
Gastrointestinal agents (5-HT4 agonist)
Interaction Rating=Minor Be watchful with this combination.
Lysine might reduce the effects of some gastrointestinal drugs called 5-HT4 agonists.
Interactions with herbs & supplements
Calcium: Lysine can increase how much calcium the body absorbs. This can increase the amount of calcium in the body. Taking lysine along with calcium might cause calcium levels to become too high.
Interactions with foods
There are no known interactions with foods.
Products
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Practitioner product
Per 37 g:
- Lysine hydrochloride 451.03 mg equiv. lysine 361 mg
- Glutamine 2.22 g
- L-leucine 1.68 g
- L-isoleucine 450 mg
- L-valine 450 mg
- L-phenylalanine 200 mg
- L-threonine 200 mg
- Cysteine hydrochloride 45 mg equiv. cysteine 31.04 mg
- L-methionine 120 mg
- L-tyrosine 112.5 mg
- Histidine hydrochloride 185.25 mg equiv. l-histidine 150 mg
- L-aspartic acid 111 mg
- L-proline 111 mg
- L-serine 27.75 mg
- Glycine 27.75 mg
- L-alanine 27.75 mg
- Taurine 11 mg
- Levocarnitine tartrate (L-carnitine) 10.99 mg equiv. levocarnitine 7.5 mg
- Potassium citrate 402.6 mg equiv. potassium 145.74 mg
- Magnesium citrate 167.09 mg equiv. magnesium 27 mg
- Magnesium glycerophosphate 49.99 mg equiv. magnesium 6.25 mg
- Calcium phosphate 62.64 mg equiv. calcium 25 mg
- Calcium glycerophosphate 393.27 mg equiv. calcium 75 mg
- Ferrous fumarate 45.6 mg equiv. iron 1.5 mg
- Manganese sulphate monohydrate 1.02 g equiv. manganese 330 µg
- Zinc sulphate monohydrate 5.74 mg equiv. zinc 2.08 mg
- Selenomethionine 28.64 µg equiv. selenium 11.54 µg
- Copper sulfate pentahydrate 656.27 µg equiv. copper 167 µg
- Molybdenum trioxide 12 µg equiv. molybdenum 8 µg
- Chromic chloride hexahydrate 46.95 µg equiv. chromium 9.16 µg
- Chromium picolinate 30.89 µg equiv. chromium 3.84 µg
- Potassium iodide 22.25 µg equiv. iodine 17 µg
- Borax 2.2 mg equiv. boron 250 µg
- Choline bitartrate 80.84 mg equiv. choline 33.25 mg
- Sodium ascorbate (Vitamin C) 22.5 mg equiv. ascorbic acid 20 mg
- dl-alpha-Tocopheryl acetate 10 mg equiv. vitamin E 10 IU
- Nicotinamide (Vitamin B3) 3.25 mg
- Retinol palmitate 418.58 µg equiv. vitamin A 767 IU
- Pyridoxine hydrochloride (Vitamin B6) 790 µg equiv. pyridoxine 650 µg
- Cholecalciferol 1.65 µg equiv. vitamin D3 66 IU
- Riboflavin (Vitamin B2) 500 µg
- Thiamine nitrate (Vitamin B1) 616.83 µg equiv. thiamine 500 µg
- Folic acid 31.27 µg
- Biotin 50 µg
- Calcium pantothenate (Vitamin B5) 3.53 mg equiv. pantothenic acid 3.25 mg
- Phytomenadione (Vitamin K1) 10 µg
- Cyanocobalamin (Vitamin B12) 2 µg
- Glucose monohydrate (Dextrose) 12.5 g
- Sunflower lecithin 250 mg
- Levomefolate glucosamine (Activated folate) 8 µg equiv. levomefolic acid 4.5 µg
- Medium Chain Triglycerides (powder) (MCT) 3 g
Practitioner product
Per 6 g (Vanilla):
- Lysine hydrochloride 250 mg equiv. lysine 200 mg
- Cholecalciferol 10 μg equiv. vitamin D3 400 IU
- Hydroxyapatite (Calcium) 200 mg equiv. calcium 50 mg equiv. phosphorus 25 mg
- Calcium phosphate 946 mg equiv. calcium 350 mg equiv. phosphorus 189 mg
- Calcium citrate 1.2 g equiv. calcium 250 mg
- Zinc citrate dihydrate 19 mg equiv. zinc 6 mg
- Manganese amino acid chelate 25 mg equiv. manganese 2.5 mg
- Borax 13 mg equiv. boron 1.5 mg
- Ascorbic acid (Vitamin C) 57 mg
- Silica - colloidal anhydrous 43 mg equiv. silicon 20 mg
- Phytomenadione (Vitamin K1) 40 μg
- Magnesium phosphate 990 mg equiv. magnesium 205 mg
- Magnesium citrate 217 mg equiv. magnesium 35 mg
Practitioner product
Per tablet:
- Lysine hydrochloride 50 mg equiv. lysine 40 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg equiv. thiamine 44.59 mg
- Riboflavin (Vitamin B2) 20 mg
- Nicotinic acid (Vitamin B3) 5 mg
- Nicotinamide (Vitamin B3) 220 mg
- Calcium pantothenate (Vitamin B5) 100 mg equiv. pantothenic acid 91.61 mg equiv. calcium 8.39 mg
- Pyridoxine hydrochloride (Vitamin B6) 50 mg equiv. pyridoxine 41.14 mg
- Cyanocobalamin (Vitamin B12) 100 μg
- Retinol acetate 884.62 μg equiv. vitamin A 750 μg RE
- Folic acid 150 μg
- Ascorbic acid (Vitamin C) 50 mg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- d-alpha-Tocopheryl acid succinate 50 mg equiv. vitamin E 60.5 IU
- Biotin 50 μg
- Choline bitartrate 50 mg equiv. choline 20.56 mg
- L-glutamine 50 mg
- Inositol 25 mg
- Lecithin 50 mg
- Taurine 125 mg
- Calcium hydrogen phosphate dihydrate 50 mg equiv. calcium 11.62 mg
- Chromic chloride hexahydrate 20.5 μg equiv. chromium 4 μg
- Potassium iodide (Iodine) 40.5 μg equiv. iodine 31 μg equiv. potassium 9.54 μg
- Manganese sulphate monohydrate 500 μg equiv. manganese 162.5 μg
- Magnesium phosphate pentahydrate 33.88 mg equiv. magnesium 7 mg
- Magnesium aspartate dihydrate 10.67 mg equiv. magnesium 800 μg
- Molybdenum trioxide 69.9 μg equiv. molybdenum 46.6 μg
- Potassium phosphate tribasic 30 mg equiv. potassium 14 mg
- Potassium aspartate 13.82 mg equiv. potassium 3 mg
- Zinc gluconate 110.26 mg equiv. zinc 14.4 mg
- Beta-carotene carotenoids (Vitamin A) 6 mg
- Copper sulfate pentahydrate 23.6 μg equiv. copper 6 μg
Practitioner product
Per tablet:
- Lysine hydrochloride 35 mg equiv. lysine 27.45 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg equiv. thiamine 44.6 mg
- Nicotinamide (Vitamin B3) 220 mg
- Pyridoxine hydrochloride (Vitamin B6) 48.62 mg equiv. pyridoxine 40 mg
- Riboflavin 5-phosphate sodium (Activated B2) 27.4 mg equiv. riboflavin 20 mg
- Mecobalamin (Vitamin B12) 500 μg
- Selenomethionine 65 μg equiv. selenium 26 μg
- Retinol acetate 884 μg equiv. vitamin A 750 μg RE
- Nicotinic acid (Vitamin B3) 5 mg
- Calcium pantothenate (Vitamin B5) 100 mg equiv. pantothenic acid 91.6 mg equiv. calcium 8.4 mg
- Calcium folinate (Activated folate) 278 μg equiv. folinic acid 200 μg
- Levomefolate calcium (Activated folate) 216 μg equiv. levomefolic acid 200 μg
- Calcium ascorbate dihydrate (Vitamin C) 121.7 mg equiv. ascorbic acid 100 mg equiv. calcium 11.44 mg
- Cholecalciferol 2.5 μg equiv. vitamin D3 100 IU
- d-alpha-Tocopheryl acid succinate 28 mg equiv. vitamin E 34 IU
- Tocopherols concentrate - mixed (low-alpha type) 13.5 mg
- R,S-alpha lipoic acid 10 mg
- Biotin 150 μg
- Ananas comosus (Bromelain) 6 mg
- Choline bitartrate 40 mg
- Cysteine hydrochloride monohydrate 21.74 mg equiv. cysteine 15 mg
- L-glutamine 40 mg
- Citrus bioflavonoids extract 5 mg
- Inositol 25 mg
- Lecithin 15 mg
- Rutin (Rutoside) 10 mg
- Taurine 85 mg
- Chromium nicotinate 205 μg equiv. chromium 25 μg
- Potassium iodide (Iodine) 41 μg equiv. iodine 31 μg equiv. potassium 9.6 μg
- Magnesium phosphate pentahydrate 50 mg equiv. magnesium 10 mg
- Manganese amino acid chelate 250 μg equiv. manganese 50 μg
- Potassium phosphate dibasic 31.82 mg equiv. potassium 14 mg
- Zinc amino acid chelate 72 mg equiv. zinc 14.4 mg
- Molybdenum trioxide 75 μg equiv. molybdenum 50 μg
- Rosa canina ext. 10 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 10 mg equiv. pyridoxine 6.38 mg
- Citrus bioflavonoids extract 5 mg
- Copper gluconate 43 μg equiv. copper 6 μg
Practitioner product
Per tablet:
- Lysine hydrochloride 18.75 mg equiv. lysine 15 mg
- Riboflavin (Vitamin B2) 2 mg
- Hydroxocobalamin (Vitamin B12) 100 µg
- Leonurus cardiaca ext. 50 mg
- Calcium pantothenate (Vitamin B5) 10.9 mg equiv. pantothenic acid 10 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 3.1 mg equiv. pyridoxine 2 mg
- Cholecalciferol 2 µg equiv. vitamin D3 80 IU
- Choline bitartrate 60.8 mg equiv. choline 25 mg
- Magnesium glycinate dihydrate 213.7 mg equiv. magnesium 25 mg
- Copper (II) glycinate 1.67 mg equiv. copper 500 µg
- Taurine 50 mg
- L-ornithine monohydrochloride 19.1 mg equiv. ornithine 15 mg
- L-methionine 15 mg
- Ubidecarenone (Coenzyme Q10) 25 mg
- Passiflora incarnata ext. 150 mg
- Schisandra chinensis ext. 25 mg
- Camellia sinensis ext. 25 mg
- Piper nigrum ext. 12 µg
- Biotin 100 µg
- Calcium glycinate 234.79 mg equiv. calcium 50 mg
Practitioner product
Per 5 g (Berry and Peach):
- Lysine hydrochloride 15 mg equiv. lysine 12 mg
- Cholecalciferol 10 μg equiv. vitamin D3 400 IU
- Retinyl acetate 472 μg equiv. vitamin A 400 μg
- Zinc citrate dihydrate 18.65 mg equiv. zinc 6 mg
- Palm tocotrienols complex (Vitamin E) 2.5 mg
- Hydroxocobalamin (Vitamin B12) 15 μg
- Calcium ascorbate dihydrate (Vitamin C) 60.5 mg equiv. ascorbic acid 50 mg
- Calcium citrate 1.04 g equiv. calcium 250 mg
- Magnesium citrate 802.5 mg equiv. magnesium 130 mg
- Menaquinone 7 (Vitamin K2) 5 μg
- Phytomenadione (Vitamin K1) 30 μg
- Potassium iodide 117.7 μg equiv. iodine 90 μg
- Iron bisglycinate 17.78 mg equiv. iron 4 mg
- Riboflavin 5-phosphate sodium (Activated B2) 5 mg
- Nicotinamide (Vitamin B3) 15 mg
- Calcium pantothenate (Vitamin B5) 16.4 mg equiv. pantothenic acid 15 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 1.55 mg equiv. pyridoxine 1 mg
- Biotin 25 μg
- Chromium nicotinate 120.7 μg equiv. chromium 15 μg
- Manganese amino acid chelate 2500 μg equiv. manganese 250 μg
- Molybdenum trioxide 33.75 μg equiv. molybdenum 22.5 μg
- Calcium hydrogen phosphate dihydrate 54.58 mg equiv. calcium 12.7 mg
- L-glycine 2 g
- Choline bitartrate 150 mg
- Selenomethionine 75 μg equiv. selenium 30 μg
- Thiamine hydrochloride (Vitamin B1) 5 mg equiv. thiamine 3.9 mg
- Pyridoxine hydrochloride (Vitamin B6) 4.5 mg equiv. pyridoxine 3.7 mg
- Calcium folinate (Activated folate) 215 μg equiv. folinic acid 200 μg
- Potassium citrate 27.68 mg equiv. potassium 10 mg
- Total Ascorbic acid 100 mg
Practitioner product
Per tablet:
- Lysine hydrochloride 12.5 mg equiv. lysine 10 mg
- Eleutherococcus senticosus ext. 50 mg
- Thiamine hydrochloride (Vitamin B1) 2.54 mg equiv. thiamine 2 mg
- Nicotinamide (Vitamin B3) 20 mg
- Calcium pantothenate (Vitamin B5) 9.83 mg equiv. pantothenic acid 9 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 3.14 mg equiv. pyridoxine 2 mg
- Ascorbic acid (Vitamin C) 60 mg
- d-alpha-Tocopheryl acetate (Vitamin E) 7.35 mg equiv. vitamin E 10 IU equiv. d-alpha-tocopherol 6.71 mg
- Biotin 80 µg
- Inositol 50 mg
- Quercetin 50 mg
- Potassium sulphate 78 mg equiv. potassium 35 mg
- Zinc glycinate monohydrate 10.64 mg equiv. zinc 3 mg
- Manganese (II) glycinate 3.695 mg equiv. manganese 1 mg
- Potassium iodide 91.8 µg equiv. iodine 70 µg
- Selenomethionine 50 µg equiv. selenium 20 µg
- Levomefolate glucosamine (Activated folate) 90 µg equiv. levomefolic acid 50 µg
- L-tyrosine 10 mg
- L-serine 5 mg
- Brassica oleracea var. italica ext. 37.5 mg
- Withania somnifera ext. 25 mg
- Zingiber officinale ext. 10 mg
- Capsicum annuum ext. 8.33 mg
- Piper nigrum ext. 16 µg
- Levocarnitine fumarate (L-carnitine) 178.6 mg equiv. levocarnitine 100 mg
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Practitioner product
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Per 7.2 g (Fruit Punch):
- Lysine hydrochloride 720 mg
- Sodium chondroitin sulphate (bovine) 120 mg equiv. chondroitin sulphate 108 mg
- L-leucine 240 mg
- L-valine 240 mg
- L-glycine 1.75 g
- Glucosamine hydrochloride 600 mg equiv. glucosamine 498 mg
- Glucosamine sulphate potassium chloride 600 mg equiv. potassium 155 mg equiv. glucosamine 354.7 mg
- Creatine monohydrate 600 mg
- Ascorbic acid (Vitamin C) 600 mg
- Citrus bioflavonoids extract 396 mg
- Calcium pantothenate (Vitamin B5) 36 mg equiv. pantothenic acid 33 mg
- Zinc amino acid chelate 30 mg equiv. zinc 6 mg
- Copper gluconate 4.6 mg equiv. copper 600 µg
- Selenomethionine 130 µg equiv. selenium 52.2 µg
- Borax 19.4 mg equiv. boron 2.23 mg
Practitioner product
Per tablet:
- L-lysine 50 mg
- Thiamine hydrochloride (Vitamin B1) 56 mg
- Pyridoxine hydrochloride (Vitamin B6) 50 mg equiv. pyridoxine 41 mg
- Riboflavin (Vitamin B2) 30 mg
- Cyanocobalamin (Vitamin B12) 400 μg
- Nicotinamide (Vitamin B3) 220 mg
- Calcium pantothenate (Vitamin B5) 105 mg
- Taurine 125 mg
- L-glutamine 100 mg
- Ascorbic acid (Vitamin C) 75 mg
- Potassium phosphate dibasic 71 mg equiv. potassium 32 mg
- Choline bitartrate 50 mg
- Lecithin 50 mg
- Calcium hydrogen phosphate dihydrate 52 mg equiv. calcium 12 mg
- Magnesium citrate 44 mg equiv. magnesium 7.1 mg
- Zinc sulphate monohydrate 41 mg equiv. zinc 15 mg
- Tocopherols concentrate - mixed (low-alpha type) (Vitamin E) 15 mg
- Borax 4.4 mg equiv. boron 500 μg
- Chromium nicotinate 500 μg equiv. chromium 50 μg
- Folic acid 395 μg
- Selenomethionine 62.5 μg equiv. selenium 25 μg
- Manganese amino acid chelate 113 μg equiv. manganese 18 μg
- Biotin 50 μg
- Potassium iodide (Iodine) 45.8 μg equiv. iodine 35 μg equiv. potassium 11 μg
- Copper gluconate 43 μg equiv. copper 6 μg
- Cholecalciferol 1 μg
- Iron bisglycinate 50 mg equiv. iron 10 mg
- Beta-carotene 5 mg
Practitioner product
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Practitioner product
Per capsule:
Practitioner product
Per 7 g (Lemonade):
- L-lysine
- Schisandra chinensis ext. equiv. dry 2.5 g
- L-leucine
- L-isoleucine
- L-methionine
- L-threonine
- L-valine
- L-phenylalanine
- L-histidine
- L-tryptophan
- Calcium citrate
- Magnesium bisglycinate
- Flavour
- Silica - colloidal anhydrous
- Ascorbic acid (Vitamin C)
- Potassium citrate
- Pyridoxal 5-phosphate (P5P)
- Methylcobalamin (Activated B12)
- Stevia rebaubiana
420 g Lemonade
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This monograph was last reviewed on 03/10/2024 10:00:00 and last updated on 31/10/2020 02:10:28. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
