Mangosteen
Scientific names: Garcinia mangostana
Family: Clusiaceae
Alternate names: Amibiasine, Fruit des Rois, Jus de Xango, Mang Cut, Manggis, Manggistan, Mangosta, Mangostan, Mangostán, Mangostana, Mangostanier, Mangostao, Mangostier, Mangoustan, Mangoustanier, Mangouste, Mangoustier, Manguita, Meseter, Queen of Fruits, Sementah, Semetah, Xango, Xango Juice
Actions: Anti-allergy properties, Anti-bacterial properties, Anti-fungal properties, Anti-histamine properties, Anti-inflammatory properties, Anti-oxidant activity, Anti-proliferative properties, Anti-viral properties, Enzymatic, Vascular
Background
Mangosteen (Garcinia mangostana) is a plant that grows in Southeast Asia. The fruit is dark purple or red. The fruit pulp is slightly acidic and sweet.
Mangosteen contains chemicals that might act as antioxidants and fight infections.
People use mangosteen for serious gum infections, obesity, muscle strength, diarrhea, and many other conditions, but there is no good scientific evidence to support most of these uses.
Don't confuse mangosteen with garcinia. These are not the same.
Mangosteen contains chemicals that might act as antioxidants and fight infections.
People use mangosteen for serious gum infections, obesity, muscle strength, diarrhea, and many other conditions, but there is no good scientific evidence to support most of these uses.
Don't confuse mangosteen with garcinia. These are not the same.
Safety Safety definitions
When taken by mouth: Mangosteen is possibly safe when taken for up to 12 weeks. It might cause constipation, bloating, nausea, vomiting, and tiredness.
When applied to the gums: Mangosteen gel is possibly safe.
Bleeding disorders: Mangosteen might slow blood clotting. Taking mangosteen might increase the risk of bleeding in people with bleeding disorders.
Surgery: Mangosteen might slow blood clotting. Taking mangosteen might increase the risk of bleeding during or after surgery. Stop taking mangosteen 2 weeks before surgery.
When applied to the gums: Mangosteen gel is possibly safe.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if mangosteen is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Bleeding disorders: Mangosteen might slow blood clotting. Taking mangosteen might increase the risk of bleeding in people with bleeding disorders.
Surgery: Mangosteen might slow blood clotting. Taking mangosteen might increase the risk of bleeding during or after surgery. Stop taking mangosteen 2 weeks before surgery.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- A serious gum infection (periodontitis). Taking mangosteen by mouth or applying a gel containing mangosteen to the gums might help improve gum health.
Dosing & administration
Mangosteen has most often been used by adults in doses of up to 560 mg by mouth daily, for up to 12 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Donepezil (Aricept)
Interaction Rating=Minor Be watchful with this combination.
Mangosteen might increase the effects of donepezil.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Mangosteen might slow blood clotting. Taking mangosteen along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Interactions with herbs & supplements
Herbs and supplements that might slow blood clotting: Mangosteen might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
Interactions with foods
There are no known interactions with foods.
Products
View all products
Per 6 g:
- Garcinia mangostana (Mangosteen) (fruit) powder
- Magnesium citrate
- Magnesium glycinate
- Fragaria ananassa (juice) powder (Strawberry)
- Euterpe oleracea (berry) ext. (Acai)
- Aristotelia chilensis (Maqui berry)
- Lycium barbarum (fruit)
- Glycine
- Magnesium orotate
- Potassium citrate
- Taurine
- L-glutamine
- Coconut water powder
- Beta vulgaris (root) powder (Beetroot)
- Calcium citrate
- Natural strawberry flavour
- Levocarnitine tartrate (L-carnitine)
- Curry leaf extract
- Psidium guajava (Guava)
- Citrus limon (Lemon)
- Phyllanthus emblica
- Ocimum tenuiflorum
- Bixa orellana
- Malic acid
- Silica - colloidal anhydrous
- Pyridoxine hydrochloride (Vitamin B6)
- Calcium pantothenate (Vitamin B5)
- Zinc citrate dihydrate
- Riboflavin (Vitamin B2)
- Nicotinamide (Vitamin B3)
- Thiamine hydrochloride (Vitamin B1)
- Cyanocobalamin (Vitamin B12)
- Folic acid
- Thaumatin
- Punica granatum
- Rubus idaeus (fruit) powder
Practitioner product
Per 6 g (Berry):
- Garcinia mangostana (Mangosteen) juice dry
- L-glutamine 1 g
- N-acetyl glucosamine (NAG) 1.5 g
- L-proline 750 mg
- L-threonine 1 g
- L-serine 750 mg
- Beta vulgaris (root) powder (Beetroot)
- Citric acid anhydrous
- Malic acid
- Natural strawberry flavour
- Fragaria ananassa (juice) powder (Strawberry)
- Euterpe oleracea (berry) ext. (Acai)
- Aristotelia chilensis (Maqui berry)
- Lycium chinese juice dry
- Glycine
- Silica - colloidal anhydrous
- Natural vanilla flavour
- Thaumatin
- Punica granatum
- Rubus idaeus
Practitioner product
Per 1 g:
- Garcinia mangostana (Mangosteen) (fruit)
- N-acetylcysteine (NAC) 940 mg
- Beta vulgaris (root) powder (Beetroot)
- Fragaria chiloenis (juice) powder (Beach strawberry)
- Euterpe oleracea (berry) ext. (Acai)
- Aristotelia chilensis (Maqui berry)
- Lycium barbarum (fruit)
- Natural strawberry flavour
- Thaumatin
- Silicon dioxide
- Punica granatum
- Rubus idaeus (fruit) juice
Practitioner product
Per 5 g:
- Garcinia mangostana (Mangosteen) (fruit) powder
- Inulin (Dietary fibre)
- Marine collagen peptides 250 mg
- Lepidium meyenii (root) powder
- Lactobacillus rhamnosus (LR-32)
- Bifidobacterium longum (BL-05)
- Zinc
- Cannabis sativa powder 520 mg
- Arthrospira platensis (Spirulina) 370 mg
- Linum usitatissimum (seed) flour (Flaxseed) 250 mg
- Wheatgrass powder
- Sunflower lecithin
- Citrus limon (juice) (Lemon)
- Ananas comosus (Pineapple)
- Ascorbic acid (Vitamin C)
- Euterpe oleracea (berry) ext. (Acai)
- Chlorella pyrenoidosa powder
- Lycopersicon esculentum (Tomato)
- Apple pectin
- Beta vulgaris (root) powder (Beetroot)
- Citric acid anhydrous
- Citrullus lanatus (Watermelon)
- Fragaria ananassa (juice) powder (Strawberry)
- Punica granatum juice dry
- Carica papaya (fruit) powder
- Vaccinium macrocarpon (fruit) powder
- Natural vanilla flavour
- Lycium barbarum (fruit)
- Aristotelia chilensis (Maqui berry)
- Silybum marianum powder
- Astragalus membranaceus (root) powder
- Equisetum arvense (herb) powder
- Laminaria digitara (Kelp)
- Silica - colloidal anhydrous
- Daucus carota powder (Carrot)
- Camellia sinensis powder
- Withania somnifera (root) powder
- Eleutherococcus senticosus (root) powder
- Echinacea purpurea (root) powder
- Melissa officinalis powder
- Taraxacum officinale (leaf) powder
- Zingiber officinale (root) powder
- Rosa canina powder
- Vaccinium myrtillus (fruit) powder
- Ulmus rubra (bark) powder
- Mushroom powder
- Kakadu plum powder
- Calcium pantothenate (Vitamin B5)
- Panax ginseng powder
- Curcuma longa (root) powder
- Backhousia citriodora (leaf)
- Thaumatin
- Ananas comosus (Bromelain)
- Protease
- Phyllanthus emblica (fruit) powder
- Morindae officinalis (fruit) powder
- Marine algae
- Malpighia glabra (fruit) powder
- Medicago sativa 200 mg
- Sambucus nigra (fruit)
- Vaccinium corymbosum (fruit) powder
- Hordeum vulgare powder 200 mg
- Salvia hispanica (seed) powder
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This monograph was last reviewed on 16/11/2023 11:00:00 and last updated on 09/10/2020 03:02:30. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
