Methionine
Scientific names: L-2-amino-4-(methylthio)butyric acid
Alternate names: D-Methionine, DL-Methionine, DL Methionine, DL-Méthionine, L-Methionine, L-Méthionine, Méthionine, Metionina
Actions: Anticancer, Antioxidant, Antiviral, Endocrine, Hepatic, Hormonal, Nutrient
Background
Methionine is an essential amino acid found in meat, fish, and dairy products. Amino acids are the building blocks used to make proteins.
Methionine cannot be made by the body, so it must be consumed in the diet. It plays an important role in the many functions within the body. It may also act as an antioxidant and help to protect damaged tissues.
People use methionine for preventing birth defects. It is also used for liver disorders, viral infections, breast cancer, and many other conditions, but there is no good scientific evidence to support these uses.
Methionine cannot be made by the body, so it must be consumed in the diet. It plays an important role in the many functions within the body. It may also act as an antioxidant and help to protect damaged tissues.
People use methionine for preventing birth defects. It is also used for liver disorders, viral infections, breast cancer, and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: Methionine is commonly consumed in foods. It is possibly safe when used as medicine under the supervision of a healthcare provider. But methionine is possibly unsafe when used for self-medication. Too much methionine can cause brain damage and death. Methionine can increase blood levels of homocysteine, a chemical that may cause heart disease, and might also promote the growth of some tumors.
Children: Methionine is commonly consumed in foods. There isn't enough reliable information to know if methionine is safe to use in larger amounts as medicine without the care of a healthcare provider.
Acidosis: Methionine can cause changes in acidity of the blood and should not be used in people with a condition called acidosis.
"Hardening of the arteries" (atherosclerosis): People who have atherosclerosis should not take methionine. Methionine might make atherosclerosis worse.
Liver disease, including cirrhosis: People who have liver disease should not take methionine. Methionine might make liver disease worse.
Methylenetetrahydrofolate reductase (MTHFR) deficiency: People who have this disorder should not take methionine. Methionine might make this disorder worse.
Schizophrenia: Large doses of methionine might cause confusion, agitation, and other similar symptoms in people with schizophrenia.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Methionine is commonly consumed in foods. There isn't enough reliable information to know if methionine is safe to use in larger amounts as medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.Children: Methionine is commonly consumed in foods. There isn't enough reliable information to know if methionine is safe to use in larger amounts as medicine without the care of a healthcare provider.
Acidosis: Methionine can cause changes in acidity of the blood and should not be used in people with a condition called acidosis.
"Hardening of the arteries" (atherosclerosis): People who have atherosclerosis should not take methionine. Methionine might make atherosclerosis worse.
Liver disease, including cirrhosis: People who have liver disease should not take methionine. Methionine might make liver disease worse.
Methylenetetrahydrofolate reductase (MTHFR) deficiency: People who have this disorder should not take methionine. Methionine might make this disorder worse.
Schizophrenia: Large doses of methionine might cause confusion, agitation, and other similar symptoms in people with schizophrenia.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Birth defects of the brain and spine (neural tube birth defects). Eating more methionine during pregnancy seems to lower the risk of these birth defects.
Dosing & administration
Methionine is an essential amino acid found in meat, fish, and dairy products. It's recommended that adults consume 19 mg/kg in the diet daily. Recommended amounts for children depend on age.
As medicine, there isn't enough reliable information to know what an appropriate dose of methionine might be. Speak with a healthcare provider before using.
As medicine, there isn't enough reliable information to know what an appropriate dose of methionine might be. Speak with a healthcare provider before using.
Interactions with pharmaceuticals
It is not known if Methionine interacts with any medicines. Before taking Methionine, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per 4 g:
- L-methionine 125 mg
- Brassica oleracea var. italica ext. 200 mg
- L-glutamine 750 mg
- Brassica oleracea var. italica ext. 150 mg
- Curcuma longa ext. 85 mg
- Taurine 500 mg
- Cysteine hydrochloride 181 mg equiv. cysteine 125 mg
- L-glycine 500 mg
- Choline bitartrate 250 mg
- Inositol 200 mg
- Potassium sulphate 150 mg equiv. potassium 67 mg
Practitioner product
Practitioner product
Per 37 g:
- L-methionine 120 mg
- Glutamine 2.22 g
- L-leucine 1.68 g
- Lysine hydrochloride 451.03 mg equiv. lysine 361 mg
- L-isoleucine 450 mg
- L-valine 450 mg
- L-phenylalanine 200 mg
- L-threonine 200 mg
- Cysteine hydrochloride 45 mg equiv. cysteine 31.04 mg
- L-tyrosine 112.5 mg
- Histidine hydrochloride 185.25 mg equiv. l-histidine 150 mg
- L-aspartic acid 111 mg
- L-proline 111 mg
- L-serine 27.75 mg
- Glycine 27.75 mg
- L-alanine 27.75 mg
- Taurine 11 mg
- Levocarnitine tartrate (L-carnitine) 10.99 mg equiv. levocarnitine 7.5 mg
- Potassium citrate 402.6 mg equiv. potassium 145.74 mg
- Magnesium citrate 167.09 mg equiv. magnesium 27 mg
- Magnesium glycerophosphate 49.99 mg equiv. magnesium 6.25 mg
- Calcium phosphate 62.64 mg equiv. calcium 25 mg
- Calcium glycerophosphate 393.27 mg equiv. calcium 75 mg
- Ferrous fumarate 45.6 mg equiv. iron 1.5 mg
- Manganese sulphate monohydrate 1.02 g equiv. manganese 330 µg
- Zinc sulphate monohydrate 5.74 mg equiv. zinc 2.08 mg
- Selenomethionine 28.64 µg equiv. selenium 11.54 µg
- Copper sulfate pentahydrate 656.27 µg equiv. copper 167 µg
- Molybdenum trioxide 12 µg equiv. molybdenum 8 µg
- Chromic chloride hexahydrate 46.95 µg equiv. chromium 9.16 µg
- Chromium picolinate 30.89 µg equiv. chromium 3.84 µg
- Potassium iodide 22.25 µg equiv. iodine 17 µg
- Borax 2.2 mg equiv. boron 250 µg
- Choline bitartrate 80.84 mg equiv. choline 33.25 mg
- Sodium ascorbate (Vitamin C) 22.5 mg equiv. ascorbic acid 20 mg
- dl-alpha-Tocopheryl acetate 10 mg equiv. vitamin E 10 IU
- Nicotinamide (Vitamin B3) 3.25 mg
- Retinol palmitate 418.58 µg equiv. vitamin A 767 IU
- Pyridoxine hydrochloride (Vitamin B6) 790 µg equiv. pyridoxine 650 µg
- Cholecalciferol 1.65 µg equiv. vitamin D3 66 IU
- Riboflavin (Vitamin B2) 500 µg
- Thiamine nitrate (Vitamin B1) 616.83 µg equiv. thiamine 500 µg
- Folic acid 31.27 µg
- Biotin 50 µg
- Calcium pantothenate (Vitamin B5) 3.53 mg equiv. pantothenic acid 3.25 mg
- Phytomenadione (Vitamin K1) 10 µg
- Cyanocobalamin (Vitamin B12) 2 µg
- Glucose monohydrate (Dextrose) 12.5 g
- Sunflower lecithin 250 mg
- Levomefolate glucosamine (Activated folate) 8 µg equiv. levomefolic acid 4.5 µg
- Medium Chain Triglycerides (powder) (MCT) 3 g
Practitioner product
Per tablet:
- L-methionine 100 mg
- Curcumin (Turmeric) equiv. curcuminoids 9 mg
- Choline bitartrate 200 mg
- Inositol 150 mg
- Glutamine 100 mg
- Magnesium citrate 370.4 mg equiv. magnesium 60 mg
- Taurine 100 mg
- Potassium sulphate 60.2 mg equiv. potassium 27 mg
- L-glycine 100 mg
- Cysteine hydrochloride 65 mg equiv. cysteine 50 mg
- Zinc citrate dihydrate 16 mg equiv. zinc 5 mg
- Selenomethionine 124 μg equiv. selenium 50 μg
- Pyridoxal 5-phosphate monohydrate (P5P) 5.41 mg equiv. pyridoxine 3.45 mg
- Calcium folinate (Activated folate) 50 μg equiv. folinic acid 46.3 μg
- Molybdenum trioxide 37.5 μg equiv. molybdenum 25 μg
- Manganese amino acid chelate 25 mg equiv. manganese 2.5 mg
- Mecobalamin (Vitamin B12) 50 μg
- Riboflavin 5-phosphate sodium (Activated B2) 5 mg equiv. riboflavin 3.8 mg
- Tocotrienols complex - palm (Vitamin E) 1 mg
Practitioner product
Per tablet:
- L-methionine 100 mg
- Bupleurum falcatum ext. 150 mg
- Berberis vulgaris ext. 100 mg
- Taraxacum officinale ext. 100 mg
- Choline bitartrate 167 mg equiv. choline 69 mg
- Inositol 100 mg
- Taurine 100 mg
- Pyridoxine hydrochloride (Vitamin B6) 25 mg equiv. pyridoxine 20.57 mg
- Folic acid 200 μg
- Co-methylcobalamin (Vitamin B12) 200 μg
Practitioner product
Per tablet:
- L-methionine 100 mg
- L-glutamine 100 mg
- Ascorbic acid (Vitamin C) 20 mg
- Selenomethionine 124 μg equiv. selenium 50 μg
- Zinc amino acid chelate 25 mg equiv. zinc 5 mg
- Silybum marianum ext. 85.7 mg
- Brassica oleracea var. italica ext. 75 mg
- Cysteine hydrochloride 29 mg equiv. cysteine 20 mg
- L-glycine 150 mg
- Taurine 200 mg
- Choline bitartrate 200 mg
- Inositol 100 mg
- L-ornithine monohydrochloride 10 mg equiv. ornithine 7.84 mg
- Citrus bioflavonoids extract 30 mg
- Molybdenum trioxide 60 μg equiv. molybdenum 40 μg
- Copper gluconate 42.86 μg equiv. copper 6 μg
- Pyridoxal 5-phosphate (P5P) 7.84 mg equiv. pyridoxine 5 mg
- Calcium folinate (Activated folate) 69.44 μg equiv. folinic acid 50 μg
- Cyanocobalamin (Vitamin B12) 50 μg
- Glutathione 20 mg
- Manganese amino acid chelate 250 μg equiv. manganese 25 μg
Practitioner product
Per capsule:
- L-methionine 50 mg
- Silybum marianum ext. 171.43 mg
- Taraxacum officinale ext. 50 mg
- Taurine 100 mg
- Mentha x piperita oil 4 mg
- Choline bitartrate 150 mg
- Inositol 100 mg
- Folic acid 99 μg
- Calcium folinate (Activated folate) 108 μg equiv. folinic acid 100 μg
- Cyanocobalamin (Vitamin B12) 100 μg
- Total Pyridoxine 5.5 mg
Practitioner product
Per tablet:
- L-methionine 15 mg
- Riboflavin (Vitamin B2) 2 mg
- Hydroxocobalamin (Vitamin B12) 100 µg
- Leonurus cardiaca ext. 50 mg
- Calcium pantothenate (Vitamin B5) 10.9 mg equiv. pantothenic acid 10 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 3.1 mg equiv. pyridoxine 2 mg
- Cholecalciferol 2 µg equiv. vitamin D3 80 IU
- Choline bitartrate 60.8 mg equiv. choline 25 mg
- Magnesium glycinate dihydrate 213.7 mg equiv. magnesium 25 mg
- Copper (II) glycinate 1.67 mg equiv. copper 500 µg
- Taurine 50 mg
- L-ornithine monohydrochloride 19.1 mg equiv. ornithine 15 mg
- Lysine hydrochloride 18.75 mg equiv. lysine 15 mg
- Ubidecarenone (Coenzyme Q10) 25 mg
- Passiflora incarnata ext. 150 mg
- Schisandra chinensis ext. 25 mg
- Camellia sinensis ext. 25 mg
- Piper nigrum ext. 12 µg
- Biotin 100 µg
- Calcium glycinate 234.79 mg equiv. calcium 50 mg
Practitioner product
Practitioner product
Per 10 g (Berry):
- L-methionine
- Schisandra chinensis
- Berberis vulgaris
- Cynara scolymus
- Silybum marianum
- Passionfruit
- Citrus limon (Lemon)
- Piper nigrum
- Zingiber officinale
- Camellia sinensis
- Beta vulgaris
- Ribes nigrum
- L-glutamine
- L-glycine
- Zinc gluconate
- Taurine
- Choline bitartrate
- Pyridoxine hydrochloride (Vitamin B6)
- Folic acid
- Selenomethionine
- Cyanocobalamin (Vitamin B12)
- Apple pectin
- Riboflavin (Vitamin B2)
- Natural flavours
- Rosmarinus officinalis
- Echinacea angustifolia
- Malpighia glabra
- Curcuma longa
- L-cysteine
- Oryza sativa (Rice hulls)
- Silicon dioxide
- Punica granatum
- Vaccinium corymbosum (fruit) powder
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Per 7 g (Lemonade):
- L-methionine
- Schisandra chinensis ext. equiv. dry 2.5 g
- L-leucine
- L-isoleucine
- L-threonine
- L-valine
- L-lysine
- L-phenylalanine
- L-histidine
- L-tryptophan
- Calcium citrate
- Magnesium bisglycinate
- Flavour
- Silica - colloidal anhydrous
- Ascorbic acid (Vitamin C)
- Potassium citrate
- Pyridoxal 5-phosphate (P5P)
- Methylcobalamin (Activated B12)
- Stevia rebaubiana
420 g Lemonade
RRP: $99.95$89.96Save: 10%
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Per 12 g (Juicy Peach):
- Total Amino blend Amino9™ 2 g
- L-methionine
- L-leucine 2 g
- L-valine 1 g
- L-isoleucine 1 g
- L-histidine
- L-isoleucine
- L-leucine
- L-lysine
- L-phenylalanine
- L-threonine
- L-valine
- L-tryptophan
- L-glutamine 1 g
- Sodium chloride (Salt)
- Potassium chloride
- Calcium citrate
- Magnesium sulphate
- Ananas comosus (Bromelain) 25 mg
- Natural flavours
- Citric acid monohydrate
- Stevia rebaubiana
- Polyphenolic fulvic minerals 10 mg
- Tart cherry extract 250 mg
- Curcuma longa 50 mg
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Per 30 g (Tropical Crush):
- L-methionine
- Hydrolysed pea protein
- L-alanine
- Glycine
- L-valine
- L-leucine
- L-isoleucine
- L-proline
- L-phenylalanine
- L-tyrosine
- L-serine
- L-threonine
- L-arginine
- L-histidine
- L-lysine
- L-aspartic acid
- L-glutamic acid
- L-tryptophan
- L-cysteine
- Natural flavours
- Cichorium intybus (root) (Chicory)
- Acacia sp. (gum)
- Coconut water powder
- Medium chain triglycerides (MCT)
- Potassium citrate
- Magnesium citrate
- Sodium chloride (Salt)
- Calcium citrate
- Ascorbic acid (Vitamin C)
- Citric acid anhydrous
- Stevia rebaubiana
- Thaumatin
- Beta-carotene
- Riboflavin (Vitamin B2)
$59.95
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Per 30 g (Chocolate):
- Egg albumen powder
- Natural flavours
- Stevia rebaubiana
- Theobroma cacao
900 g Chocolate
RRP: $74.94$61.83Save: 17%
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Per 33 g (Banana Ice-Cream):
RRP: $79.99$70.39Save: 12%
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RRP: $49.95$43.96Save: 12%
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RRP: $49.95$41.21Save: 17%
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Per 48 g:
- Whey protein concentrate
- Whey protein isolate
- Soy lecithin
- Theobroma cacao (Cocoa powder)
- Medium Chain Triglycerides (powder) (MCT)
- Calcium phosphate dibasic
- Flavour
- Magnesium citrate
- Cyamopsis tetragonoloba (Guar gum)
- Calcium citrate
- Zinc gluconate
- Ascorbic acid (Vitamin C)
- Beta-carotene carotenoids (Vitamin A)
- Chromium chloride
- Ferrous fumarate
- d-alpha-Tocopheryl acetate
- Calcium pantothenate (Vitamin B5)
- Riboflavin (Vitamin B2)
- Sodium selenite
- Thiamine hydrochloride (Vitamin B1)
- Cyanocobalamin (Vitamin B12)
- Biotin
- Potassium iodide
- Sodium molybdate
- Niacinamide (Vitamin B3)
- Copper sulfate
- Manganese citrate
- Cholecalciferol
- Folic acid
- Pyridoxine hydrochloride (Vitamin B6)
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This monograph was last reviewed on 12/04/2024 10:00:00 and last updated on 12/09/2022 02:49:16. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
