Ornithine
Scientific names: L-5-aminorvaline, L-2,5-diaminovaleric acid
Alternate names: Chlorhydrate d'Ornithine, L-Ornithine, L-Ornithine HCl, L-Ornithine Hydrochloride, Ornithine HCl, Ornitina
Actions: Anabolic, Antiobesity, Immune, Urea cycle, Wound-healing
Background
Ornithine is an amino acid that is made in the body. It's not used to create protein, but plays a role in other processes. It can also be made in a lab.
Ornithine might help to increase levels of another amino acid called arginine. It might also increase levels of hormones that increase muscle size.
People use ornithine for athletic performance, dry skin, insomnia, wound healing, and other purposes, but there is no good scientific evidence to support most of these uses.
Don't confuse ornithine with ornithine alpha-ketoglutarate (OKG) or L-Ornithine-L-Aspartate. These are not the same.
Ornithine might help to increase levels of another amino acid called arginine. It might also increase levels of hormones that increase muscle size.
People use ornithine for athletic performance, dry skin, insomnia, wound healing, and other purposes, but there is no good scientific evidence to support most of these uses.
Don't confuse ornithine with ornithine alpha-ketoglutarate (OKG) or L-Ornithine-L-Aspartate. These are not the same.
Safety Safety definitions
When taken by mouth: Ornithine is possibly safe when used at doses up to 500 mg daily for up to 8 weeks and up to 12 grams daily for 4 weeks. It might cause stomach or intestine symptoms.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if ornithine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Athletic performance. Taking ornithine by mouth might reduce fatigue and improve some measures of athletic performance.
Dosing & administration
There isn't enough reliable information to know what an appropriate dose of ornithine might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Interactions with pharmaceuticals
It is not known if Ornithine interacts with any medicines. Before taking Ornithine, talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per tablet:
- L-ornithine monohydrochloride 255.07 mg equiv. ornithine 200 mg
- L-tyrosine 100 mg
- Phosphatidylserine enriched soy (powder) (Lecithin) 141.43 mg equiv. phosphatidylserine 100 mg
- Calcium pantothenate (Vitamin B5) 75 mg equiv. pantothenic acid 68.71 mg equiv. calcium 6.29 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 25 mg equiv. pyridoxine 15.95 mg
Practitioner product
Per capsule:
Practitioner product
Per tablet:
- L-ornithine monohydrochloride 19.1 mg equiv. ornithine 15 mg
- Riboflavin (Vitamin B2) 2 mg
- Hydroxocobalamin (Vitamin B12) 100 µg
- Leonurus cardiaca ext. 50 mg
- Calcium pantothenate (Vitamin B5) 10.9 mg equiv. pantothenic acid 10 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 3.1 mg equiv. pyridoxine 2 mg
- Cholecalciferol 2 µg equiv. vitamin D3 80 IU
- Choline bitartrate 60.8 mg equiv. choline 25 mg
- Magnesium glycinate dihydrate 213.7 mg equiv. magnesium 25 mg
- Copper (II) glycinate 1.67 mg equiv. copper 500 µg
- Taurine 50 mg
- Lysine hydrochloride 18.75 mg equiv. lysine 15 mg
- L-methionine 15 mg
- Ubidecarenone (Coenzyme Q10) 25 mg
- Passiflora incarnata ext. 150 mg
- Schisandra chinensis ext. 25 mg
- Camellia sinensis ext. 25 mg
- Piper nigrum ext. 12 µg
- Biotin 100 µg
- Calcium glycinate 234.79 mg equiv. calcium 50 mg
Practitioner product
Per tablet:
- L-ornithine monohydrochloride 10 mg equiv. ornithine 7.84 mg
- L-glutamine 100 mg
- Ascorbic acid (Vitamin C) 20 mg
- Selenomethionine 124 μg equiv. selenium 50 μg
- Zinc amino acid chelate 25 mg equiv. zinc 5 mg
- Silybum marianum ext. 85.7 mg
- Brassica oleracea var. italica ext. 75 mg
- Cysteine hydrochloride 29 mg equiv. cysteine 20 mg
- L-glycine 150 mg
- Taurine 200 mg
- L-methionine 100 mg
- Choline bitartrate 200 mg
- Inositol 100 mg
- Citrus bioflavonoids extract 30 mg
- Molybdenum trioxide 60 μg equiv. molybdenum 40 μg
- Copper gluconate 42.86 μg equiv. copper 6 μg
- Pyridoxal 5-phosphate (P5P) 7.84 mg equiv. pyridoxine 5 mg
- Calcium folinate (Activated folate) 69.44 μg equiv. folinic acid 50 μg
- Cyanocobalamin (Vitamin B12) 50 μg
- Glutathione 20 mg
- Manganese amino acid chelate 250 μg equiv. manganese 25 μg
Practitioner product
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Practitioner product
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Practitioner product
Per 5 g serve (Forest Berry):
- L-Ornithine 250 mg
- Crocus sativus ext. 15 mg
- Melissa officinalis ext. 150 mg
- Bacopa monnieri ext. 250 mg
- Ascorbic acid (Vitamin C) 60 mg
- Calcium pantothenate (Vitamin B5) 5.45 mg equiv. pantothenic acid 5 mg
- Magnesium citrate 776 mg equiv. magnesium 112.5 mg
- Potassium citrate 104.5 mg equiv. potassium 40 mg
- L-cysteine 30 mg
- L-glycine 1.48 g
- Inositol 62.5 mg
- Phosphatidylserine enriched soy (powder) (Lecithin) 75 mg equiv. phosphatidylserine 37.5 mg
- Taurine 250 mg
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This monograph was last reviewed on 08/03/2024 11:00:00 and last updated on 25/09/2022 05:40:14. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
