Pangamic acid
Alternate names: Acide Pangamique, Ácido Pangámico, Calcium Pangamate, Calgam, Di-isopropylamine Dichloroacetate, Vitamin B15, Vitamine B15
Background
Pangamic acid is a term used for many different chemicals. It was originally claimed to contain D-gluconodimethyl aminoacetic acid from apricot kernels.
There is no standard chemical identity for pangamic acid, so it's not clear how it works. Pangamic acid is also sometimes referred to as vitamin B15, but pangamic acid is not recognized as a vitamin.
People use pangamic acid for asthma, alcohol use disorder, high cholesterol, athletic performance, and many other conditions, but there is no good scientific evidence to support these uses. Using pangamic acid may also be unsafe.
There is no standard chemical identity for pangamic acid, so it's not clear how it works. Pangamic acid is also sometimes referred to as vitamin B15, but pangamic acid is not recognized as a vitamin.
People use pangamic acid for asthma, alcohol use disorder, high cholesterol, athletic performance, and many other conditions, but there is no good scientific evidence to support these uses. Using pangamic acid may also be unsafe.
Safety Safety definitions
When taken by mouth: Pangamic acid is possibly unsafe. Chemicals found in some formulations of pangamic acid may cause cancer.
Special Precautions & Warnings:
Pregnancy and breast-feeding: It is possibly unsafe to use pangamic acid while pregnant or breast-feeding. Chemicals found in some pangamic acid formulations can cause birth defects and/or cancer. Stay on the safe side and avoid use.Effectiveness
Effective Effectiveness definitions
There is interest in using pangamic acid for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Dosing & administration
Pangamic acid is a term used for many different chemicals. There isn't enough reliable information to know what an appropriate dose might be. Chemicals found in some formulations of pangamic acid might be unsafe. Speak with your healthcare provider before taking pangamic acid.
Interactions with pharmaceuticals
Pangamic acid is a term used for many different chemicals. The risk for interactions will depend on the chemical found in a specific product. Before taking pangamic acid, speak with your healthcare provider if you take any medications.
Interactions with herbs & supplements
Pangamic acid is a term used for many different chemicals. The risk for interactions will depend on the chemical found in a specific product. Before taking pangamic acid, speak with your healthcare provider if you take any other supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 29/12/2022 18:04:43 and last updated on 21/04/2022 07:47:34. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
