Picamilon
Scientific names: Nicotinoyl-gamma-aminobutyric acid
Alternate names: Isonicotinoyl-GABA, Isonicotinoyl-Gamma-Aminobutyric Acid, N-Nicotinoyl-GABA, N-Nicotinoyl-Gamma-Aminobutyric Acid, N-Nicotinoyl-R-Aminobutyric Acid, Nicotinyl-Gamma-Aminobutyric Acid, Pikamilon, Pikamilone, Pikatropin, Pycamilon
Actions: General, Anticonvulsant, Anxiolytic, Blood-brain barrier, Cerebrovascular
Background
Picamilon is a chemical made in a lab. Once it has entered the body, it's broken down into gamma-aminobutyric acid and niacin, which are both dietary supplements. However, picamilon isn't a dietary supplement. It's used as a prescription drug in Russia. In the United States, picamilon hasn't been approved as a prescription drug, and supplements containing picamilon are banned.
Picamilon is used for anxiety, stress, mental alertness, athletic performance, and many other conditions, but there is no good scientific evidence to support these uses.
Picamilon is used for anxiety, stress, mental alertness, athletic performance, and many other conditions, but there is no good scientific evidence to support these uses.
Safety Safety definitions
When taken by mouth: There isn't enough reliable information to know if picamilon is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if picamilon is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Insufficient evidence Effectiveness definitions
- A group of eye disorders that can lead to vision loss (glaucoma). Early research shows that picamilon might improve vision in people with open-angle glaucoma.
- Loss of bladder control in people with brain, spinal cord, or nerve injuries (neurogenic bladder). Early research shows that picamilon might improve bladder control in children with neurogenic bladder.
- Anxiety.
- Athletic performance.
- Memory and thinking skills (cognitive function).
- Mental alertness.
- Seizure disorder (epilepsy).
- Stress.
- Other conditions.
Dosing & administration
The appropriate dose of picamilon depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for picamilon. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Interactions with pharmaceuticals
Niacin
Interaction Rating=Moderate Be cautious with this combination.
Taking picamilon with niacin might increase the risk for side effects from niacin.
Interactions with herbs & supplements
Gamma-aminobutyric acid (GABA): Taking picamilon with GABA might increase the risk for side effects from GABA.
Niacin: Taking picamilon with niacin might increase the risk for side effects from niacin.
Niacin: Taking picamilon with niacin might increase the risk for side effects from niacin.
Interactions with foods
There are no known interactions with foods.
Action
Picamilon is broken down into gamma-aminobutyric acid (GABA) and niacin. GABA can decrease anxiety and seizures. Niacin can improve blood flow in the brain by causing blood vessels in the brain to become more open. But there is no good scientific evidence showing that picamilon has these same effects.
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This monograph was last reviewed on 17/10/2023 11:00:00. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
