Polypodium leucotomos
Polypodium leucotomos

Background

Polypodium leucotomos is a tropical fern from Central and South America. It's been used in traditional medicines.

Polypodium leucotomos contains chemicals that might have antioxidant effects. The antioxidants in Polypodium leucotomos might prevent damage caused by excessive sun exposure.

People use Polypodium leucotomos for sunburn, eczema, dark skin patches on the face, cancer, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: Polypodium leucotomos extract is possibly safe when used in doses of 360-480 mg daily for up to 6 months. It seems to be well-tolerated.

When applied to the skin: Polypodium leucotomos extract is possibly safe when used short-term.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if Polypodium leucotomos is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Polypodium leucotomos extract is possibly safe when taken by mouth at varying doses by age for up to 6 months.

Effectiveness

There is interest in using Polypodium leucotomos for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

Polypodium leucotomos has most often been used by adults in doses of 360-960 mg by mouth daily for 2-26 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Interactions with pharmaceuticals

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Interaction Rating=Minor Be watchful with this combination.

Some medications are changed and broken down by the liver. Polypodium leucotomos might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Interactions with herbs & supplements

There are no known interactions with herbs and supplements.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 08/03/2024 11:00:00 and last updated on 25/11/2014 18:24:36. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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