
Royal jelly
Alternative names: Bee Saliva, Bee Spit, Gelée Royale, Honey Bee Milk, Jalea Real, Lait des Abeilles, Royal Bee Jelly
Actions: Adipocyte, Antiaging, Antiallergy, Antiarrhythmic, Antidiabetic, Anti-inflammatory, Antimicrobial, Antineoplastic, Antioxidant, Chemoprotective, Circulatory, Dermatological, Exercise performance, Hepatoprotective, Hormonal, Hypolipidemic, Hypotensive, Immune, Neuroprotective, Vasodilating, Weight, Wound-healing
Background
Royal jelly is a milky secretion made by worker honeybees (Apis mellifera). It's rich in carbs, protein, amino acids, fatty acids, vitamins, and minerals.
Royal jelly gets its name because it is used as food for the queen bee. Its composition varies depending on geography and climate.
People use royal jelly for symptoms of menopause. It's also used for hay fever, diabetes, premenstrual syndrome (PMS), obesity, dry eye, and many other purposes, but there is no good scientific evidence to support these uses.
Don't confuse royal jelly with bee pollen, beeswax, bee venom, honey, or propolis. Also don't confuse it with apitherapy. These are not the same.
Royal jelly gets its name because it is used as food for the queen bee. Its composition varies depending on geography and climate.
People use royal jelly for symptoms of menopause. It's also used for hay fever, diabetes, premenstrual syndrome (PMS), obesity, dry eye, and many other purposes, but there is no good scientific evidence to support these uses.
Don't confuse royal jelly with bee pollen, beeswax, bee venom, honey, or propolis. Also don't confuse it with apitherapy. These are not the same.
Safety Safety definitions
When taken by mouth: Royal jelly is possibly safe when used short-term. Doses of up to 4.8 grams daily have been used safely for up to 1 year. It's usually well-tolerated. But people with asthma or allergies might experience an allergic reaction.
When applied to the skin: Royal jelly is possibly safe when used for up to 6 months. It might cause skin irritation and rash in some people.
Children: Royal jelly is possibly safe when taken by mouth for up to 6 months in children 5-16 years of age.
Asthma or allergies: Don't use royal jelly if you have asthma or allergies to bee products. It could cause some serious reactions, even death.
When applied to the skin: Royal jelly is possibly safe when used for up to 6 months. It might cause skin irritation and rash in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if royal jelly is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Royal jelly is possibly safe when taken by mouth for up to 6 months in children 5-16 years of age.
Asthma or allergies: Don't use royal jelly if you have asthma or allergies to bee products. It could cause some serious reactions, even death.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Symptoms of menopause. Taking royal jelly by mouth, alone or with other ingredients, seems to somewhat improve symptoms of menopause. But it's not clear if applying royal jelly to the skin helps.
Possibly ineffective Effectiveness definitions
- Hay fever. Taking royal jelly by mouth before and during pollen season doesn't seem to improve seasonal allergies.
- Diabetes. Taking royal jelly by mouth doesn't seem to improve blood sugar levels in people with diabetes.
- Physical performance in elderly adults. Taking royal jelly by mouth doesn't seem to improve hand grip strength, walking, or balance in elderly people living in a nursing home.
Dosing & administration
Royal jelly has most often been used by adults in doses of 1000 mg by mouth daily for up to 6 months. It's also been applied to the skin in different types of products, including fresh royal jelly, vaginal creams, vaginal solutions, and ointments. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
Interactions with pharmaceuticals
Medications for high blood pressure (Antihypertensive drugs)
Interaction Rating=Moderate Be cautious with this combination.
Royal jelly might lower blood pressure. Taking royal jelly along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.
Warfarin (Coumadin)
Interaction Rating=Moderate Be cautious with this combination.
Royal jelly might increase the effects of warfarin. Taking royal jelly with warfarin might increase the risk of bruising or bleeding.
Interactions with herbs & supplements
Herbs and supplements that might lower blood pressure: Royal jelly might lower blood pressure. Taking it with other supplements that have the same effect might cause blood pressure to drop too much. Examples of supplements with this effect include andrographis, casein peptides, L-arginine, niacin, and stinging nettle.
Interactions with foods
There are no known interactions with foods.
Products
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Per tablet (Berry):
- Cholecalciferol 6.25 µg equiv. vitamin D3 250 IU
- d-alpha-Tocopherol 5 mg equiv. vitamin E 7.5 IU
- Co-methylcobalamin (Vitamin B12) 100 µg
- Zinc citrate 18.30 mg equiv. zinc 6.25 mg
- Calcium ascorbate (Vitamin C) 18.15 mg equiv. ascorbic acid 15 mg
- Phyllanthus emblica ext. 5 mg
- Menaquinone 7 (Vitamin K2) 20 µg
- Thiamine hydrochloride (Vitamin B1) 794 µg equiv. thiamine 625 µg
- Riboflavin 5-phosphate sodium (Activated B2) 855 µg equiv. riboflavin 625 µg
- Nicotinamide (Vitamin B3) 6.25 mg
- Calcium pantothenate (Vitamin B5) 2.98 mg equiv. pantothenic acid 2.5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 1.01 mg equiv. pyridoxine 625 µg
- Levomefolate glucosamine (Activated folate) 370.37 µg equiv. levomefolic acid 200 µg
- Ferric pyrophosphate 5 mg
- Chromium picolinate 80.45 µg equiv. chromium 10 µg
- Copper sulfate pentahydrate 392.8 µg equiv. copper 100 µg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 62.09 µg equiv. selenium 25 µg
- Borax 3.29 mg equiv. boron 375 µg
- Lutein 500 µg
- Lycopene 500 µg
- Lysine hydrochloride 3.12 mg equiv. lysine 2.5 mg
- Ascophyllum nodosum 9.34 mg
- Magnesium 6.25 mg
- Magnesium ascorbate (Vitamin C) 7.07 mg equiv. ascorbic acid 5 mg
- Calcified lithothamnion (Red algae) 13.22 mg equiv. calcium 4.17 mg
- Calcium ascorbate equiv. calcium 1.83 mg
- Calcium pantothenate equiv. calcium 0.25 mg
- Cruciferous vegetable blend 20 mg
- Ultra fruit blend 20 mg
- Live vegetable blend 20 mg
- Multi herb blend 20 mg
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Per capsule:
- Ganoderma lucidum ext. 76.8 mg
- Cordyceps sinensis ext. 76.8 mg
- Grifola frondosa ext. 76.8 mg
- Lentinula edodes ext. 76.8 mg
- Trametes versicolor ext. 76.8 mg
- Polyporus umbellatus ext. 38.4 mg
- Tremella fuciformis ext. 38.4 mg
- Poria cocos ext. 38.4 mg
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Per 10 g (Berry):
- Acacia sp. (gum) 2.5 g
- Cyamopsis tetragonoloba (Guar gum) 2 g
- Green banana starch 1.5 g
- Saccharomyces cerevisiae (boulardii) (SB) 5 billion CFU equiv. inactive (zinc powder) 24 mg
- L-glutamine 1.9 g
- Althaea officinalis ext. 500 mg
- Cinnamon zeylanicum powder 400 mg
- Protease
- Amylase enzyme
- Lipase
- Cellulase
- Lactase
- Berry flavour
- Bacillus coagulans 2 billion CFU
- Aloe barbadensis ext. 100 mg
- Punica granatum ext. 100 mg
- Natural vanilla flavour
- Malpighia glabra powder 50 mg
- Stevia rebaubiana powder 50 mg
- Beta vulgaris (root) powder (Beetroot) 33 mg
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Per tablet:
- Methylcobalamin (Activated B12) 200 μg
- Calcium ascorbate (Vitamin C) 30.25 mg equiv. ascorbic acid 25 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg
- Zinc citrate 200 mg equiv. zinc 36.6 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Thiamine hydrochloride (Vitamin B1) 1.59 mg equiv. thiamine 1.25 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Magnesium ascorbate (Vitamin C) 21.87 mg equiv. ascorbic acid 15.33 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Phyllanthus emblica ext. 9.35 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Calcified lithothamnion (Red algae) 31.52 mg equiv. calcium 9.46 mg
- Magnesium 12.5 mg
- Chromium picolinate 1.61 mg equiv. chromium 200 μg
- Copper sulfate 2 mg
- Ascophyllum nodosum 18.75 mg
- Manganese gluconate 21.93 mg equiv. manganese 2.5 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.6 mg equiv. boron 750 μg
- Lutein 1 mg
- Lycopene 1 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Cruciferous vegetable blend 25 mg
- Ultra fruit blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
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Per capsule:
- Nicotinamide mononucleotide (NMN) 500 mg
- Dimethylglycine hydrochloride (DMG) 250 mg
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Per tablet:
- Methylcobalamin (Activated B12) 200 μg
- Calcium ascorbate 30.25 mg equiv. calcium 3.04 mg equiv. ascorbic Acid 25 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg equiv. vitamin E 15 IU
- Zinc citrate 21.96 mg equiv. zinc 7.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Thiamine hydrochloride (Vitamin B1) 3.18 mg equiv. thiamine 2.5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Magnesium ascorbate (Vitamin C) 20.44 mg equiv. ascorbic acid 15.33 mg equiv. magnesium 2.19 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Calcified lithothamnion (Red algae) 73.19 mg equiv. calcium 21.96 mg
- Phyllanthus emblica ext. 9.35 mg
- Iron (II) glycinate 50 mg equiv. iron 10 mg
- Chromium picolinate 201.13 μg equiv. chromium 25 μg
- Cupric sulfate 2 mg equiv. copper 0.2 mg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.58 mg equiv. boron 0.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Ascophyllum nodosum 18.75 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Magnesium citrate 22.25 mg equiv. magnesium 3.61 mg
- Magnesium aspartate 25.49 mg equiv. magnesium 5.1 mg
- Cruciferous vegetable blend
- Ultra fruit blend
- Live vegetable blend
- Multi herb blend
- Curcumin (Turmeric) 500 μg
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Per tablet:
- Calcium ascorbate 60.49 mg equiv. calcium 6.088 mg equiv. ascorbic Acid 50 mg
- Cholecalciferol 12.5 µg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg equiv. vitamin E 15 IU
- Methylcobalamin (Activated B12) 200 µg
- Zinc citrate 21.96 mg equiv. zinc 7.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Magnesium ascorbate (Vitamin C) 38.92 mg equiv. ascorbic acid 27.827 mg equiv. magnesium 3.892 mg
- Phyllanthus emblica ext. 9.35 mg
- Menaquinone 7 (Vitamin K2) 40 µg
- Thiamine hydrochloride (Vitamin B1) 6.35 mg equiv. thiamine 5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 µg equiv. levomefolic acid 250 µg
- Calcified lithothamnion (Red algae) 63.04 mg equiv. calcium 18.91 mg
- Magnesium 12.5 mg
- Chromium picolinate 201.13 µg equiv. chromium 25 µg
- Copper sulfate 200 µg
- Manganese gluconate 10.97 mg equiv. manganese 1.25 mg
- Selenomethionine 124.18 µg equiv. selenium 50 µg
- Borax 6.58 mg equiv. boron 750 µg
- Ascophyllum nodosum 18.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Alpha lipoic acid 25 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Phyllanthus emblica ext. 10 mg
- Laminaria digitara (Kelp) 5 mg
- Ultra fruit blend 25 mg
- Cruciferous vegetable blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
- Citrus sinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
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Per tablet:
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- d-alpha-Tocopherol 10 mg
- Methylcobalamin (Activated B12) 200 μg
- Zinc citrate 36.6 mg equiv. zinc 12.5 mg
- Beta-carotene carotenoids (Vitamin A) 3 mg
- Phyllanthus emblica ext. 65 mg
- Menaquinone 7 (Vitamin K2) 40 μg
- Thiamine hydrochloride (Vitamin B1) 6.35 mg equiv. thiamine 5 mg
- Riboflavin 5-phosphate sodium (Activated B2) 1.71 mg equiv. riboflavin 1.25 mg
- Nicotinamide (Vitamin B3) 12.5 mg
- Calcium pantothenate (Vitamin B5) 5.46 mg equiv. pantothenic acid 5 mg
- Pyridoxal 5-phosphate (P5P) 2.03 mg equiv. pyridoxine 1.25 mg
- Levomefolate glucosamine (Activated folate) 463 μg equiv. levomefolic acid 250 μg
- Calcified lithothamnion (Red algae) 28.72 mg equiv. calcium 8.62 mg
- Magnesium 13.13 mg
- Chromium picolinate 201.13 μg equiv. chromium 25 μg
- Copper sulfate 200 μg
- Manganese gluconate 43.86 mg equiv. manganese 5 mg
- Selenomethionine 124.18 μg equiv. selenium 50 μg
- Borax 6.6 mg equiv. boron 750 μg
- Ascophyllum nodosum 18.75 mg
- Lutein 1 mg
- Lycopene 1 mg
- Serenoa repens ext. 25 mg
- Silybum marianum ext. 5 mg
- Vaccinium macrocarpon ext. 0.25 mg
- Camellia sinensis ext. 5 mg
- Schisandra chinensis ext. 5 mg
- Arthrospira platensis (Spirulina) 5 mg
- Euterpe oleracea (berry) ext. (Acai) 5 mg
- Chlorella vulgaris 5 mg
- Curcumin (Turmeric) 500 μg
- Zingiber officinale ext. 5 mg
- Laminaria digitara (Kelp) 5 mg
- Citrus sinensis ext. 5 mg
- Ultra fruit blend 25 mg
- Cruciferous vegetable blend 25 mg
- Live vegetable blend 22.5 mg
- Multi herb blend 12.5 mg
- Calcium ascorbate (Vitamin C) 38.58 mg equiv. ascorbic acid 32.5 mg equiv. calcium 3.88 mg
- Magnesium ascorbate (Vitamin C) 45.5 mg equiv. ascorbic acid 32.5 mg
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