Sceletium
Sceletium

Background

Sceletium (Sceletium tortuosum) is a succulent, ground-cover plant from South Africa. It's traditionally used as medicine in South Africa.

Sceletium has also been used to get "high." It contains chemicals that might reduce anxiety and cause sleepiness.

People sometimes use sceletium for anxiety, depression, stress, and many other conditions, but there is no good scientific evidence to support these uses.
When taken by mouth: There isn't enough reliable information to know if sceletium is safe. Side effects might include anxiety, headache, insomnia, irritability, and nausea.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if sceletium is safe to used when pregnant or breast-feeding. Stay on the safe side and avoid using.

Effectiveness

There is interest in using sceletium for a number of purposes, but there isn't enough reliable information to say whether it might be helpful.
Likely effective Effectiveness definitions
Possibly effective Effectiveness definitions
Likely ineffective Effectiveness definitions
Possibly ineffective Effectiveness definitions
Insufficient evidence Effectiveness definitions

Dosing & administration

There isn't enough reliable information to know what an appropriate dose of sceletium might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Interactions with pharmaceuticals

Sedative medications (CNS depressants)

Interaction Rating=Moderate Be cautious with this combination.

Sceletium might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking sceletium with sedative medications might cause breathing problems and/or too much sleepiness.

Interactions with herbs & supplements

Cannabis: Cannabis has psychoactive effects in the brain. Taking sceletium with cannabis might increase the psychoactive effects of cannabis.
Herbs and supplements with sedative properties: Sceletium might cause sleepiness and slowed breathing. Taking it along with other supplements with similar effects might cause too much sleepiness and/or slowed breathing in some people. Examples of supplements with this effect include hops, kava, L-tryptophan, melatonin, and valerian.

Interactions with foods

There are no known interactions with foods.
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This monograph was last reviewed on 17/12/2024 11:00:00 and last updated on 21/01/2022 07:31:17. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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