Superoxide dismutase (sod)
Scientific names: Superoxide dismutase
Alternate names: Orgotein, SOD, Super Dioxide Dismutase, Superóxido Dismutasa, Superoxydase Dismutase, Superoxyde Dismutase
Background
Superoxide dismutase (SOD) is an enzyme found in all living cells. An enzyme is a substance that speeds up certain chemical reactions in the body.
Superoxide dismutase helps break down potentially harmful oxygen molecules in cells. This might prevent damage to tissues. Some superoxide dismutase products are made from cows. Others are made from melons or created in a lab.
People use superoxide dismutase for osteoarthritis, rheumatoid arthritis (RA), heart attack, pneumonia, stress, and many other conditions, but there is no good scientific evidence to support most of these uses.
Superoxide dismutase helps break down potentially harmful oxygen molecules in cells. This might prevent damage to tissues. Some superoxide dismutase products are made from cows. Others are made from melons or created in a lab.
People use superoxide dismutase for osteoarthritis, rheumatoid arthritis (RA), heart attack, pneumonia, stress, and many other conditions, but there is no good scientific evidence to support most of these uses.
Safety Safety definitions
When taken by mouth: Superoxide dismutase is possibly safe when used for up to 6 months.
When applied to the skin: There isn't enough reliable information to know if superoxide dismutase is safe or what the side effects might be.
When applied into the eye: There isn't enough reliable information to know if superoxide dismutase is safe or what the side effects might be.
Some superoxide dismutase products come from animal sources, so there is some concern that products made from sick or diseased animals could cause health issues. But there have been no reports of people getting sick after using superoxide dismutase products taken from animals.
Children: There isn't enough reliable information to know if is safe or what the side effects might be.
When applied to the skin: There isn't enough reliable information to know if superoxide dismutase is safe or what the side effects might be.
When applied into the eye: There isn't enough reliable information to know if superoxide dismutase is safe or what the side effects might be.
Some superoxide dismutase products come from animal sources, so there is some concern that products made from sick or diseased animals could cause health issues. But there have been no reports of people getting sick after using superoxide dismutase products taken from animals.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if superoxide dismutase is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: There isn't enough reliable information to know if is safe or what the side effects might be.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Possibly effective Effectiveness definitions
- Osteoarthritis. Injecting superoxide dismutase into the joint might help reduce pain in people with osteoarthritis. Injections can only be given by a healthcare provider.
- Rheumatoid arthritis (RA). Injecting superoxide dismutase into the joint might help reduce pain and stiffness in people with RA. Injections can only be given by a healthcare provider.
Likely ineffective Effectiveness definitions
- Heart attack. Giving superoxide dismutase by IV doesn't seem to help to reduce heart damage after a heart attack. IV products can only be given by a healthcare provider.
Dosing & administration
Superoxide dismutase has most often been used by adults in doses of 140 IU by mouth daily for up to 4 months. Injection and topical products are also used. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
Interactions with pharmaceuticals
It is not known if Superoxide Dismutase (SOD) interacts with any medicines. Before taking Superoxide Dismutase (SOD), talk with your healthcare professional if you take any medications.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
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This monograph was last reviewed on 04/07/2024 10:00:00 and last updated on 10/10/2020 02:11:33. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
