Background

Tin (Sn) is a metal. It can exist by itself or as part of a tin compound. Tin compounds form when tin combines with other elements such as chloride, fluoride, sulfur, or oxygen. The most common form of tin in commercial products is called stannous fluoride.

People use tin as a mouth rinse or toothpaste for conditions such as sensitive teeth and gingivitis. It is also used for conditions such as bad breath, cavities, dry mouth, and plaque, but there is no good scientific evidence to support these uses.

Safety Safety definitions

When taken by mouth: There isn't enough reliable information to know if tin is safe or what the side effects might be when taken by mouth as a medicine. Large amounts might cause side effects such as diarrhea, stomach pain, and nausea.

When applied to the teeth: Toothpastes and other dental products containing tin are LIKELY SAFE when used appropriately. But these products might cause teeth staining.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if tin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Toothpastes and other dental products containing tin are LIKELY SAFE for children over the age of 6 years when used appropriately. There isn't enough reliable information to know if tin is safe to use by mouth or what the side effects might be.

Effectiveness

Dosing & administration

The following doses have been studied in scientific research:

APPLIED TO THE TEETH:

• For tooth sensitivity: Gel, toothpaste, or mouth rinse containing tin as stannous fluoride 0.4% has been used at least daily for at least 2 weeks.
• For a mild form of gum disease (gingivitis): Toothpastes containing tin as stannous fluoride 0.4%, as stannous fluoride 0.454% chelated to gluconate, or as stannous chloride have been used at least once daily.

Interactions with pharmaceuticals

It is not known if this product interacts with any medicines.

Before taking this product, talk with your health professional if you take any medications.

Interactions with herbs & supplements

Copper: Large amounts of tin in the diet might reduce how much copper is stored by the body. This might cause copper levels to become too low.
Iron: Large amounts of tin in the diet might reduce iron levels in the blood. This might cause iron levels to become too low.
Zinc: Large amounts of tin in the diet might reduce how much zinc is stored by the body. This might cause zinc levels to become too low.

Interactions with foods

There are no known interactions with foods.

Action

Tin fluoride seems to prevent bacteria from forming, which might prevent plaque and cavities. Tin compounds also seem to prevent the nerves around the teeth from being stimulated, which can prevent tooth sensitivity.