Tyrosine
Scientific names: Tyrosine
Alternate names: 2-Acetylamino-3-(4-Hydroxyphenyl)-Propanoic Acid, 2-Amino-3-(4-Hydroxyphenyl)propionic acid, Acetyl-L-Tyrosine, Acétyl-L-Tyrosine, L-Tyrosine, N-Acetyl L-Tyrosine, N-Acetyl-L-Tyrosine, N-Acétyl L-Tyrosine, N-Acetyl-Tyrosine, N-Acétyl-Tyrosine, Tirosina, Tyr, Tyrosinum
Actions: Antidepressant, Antistress
Background
Tyrosine is a type of amino acid, which are the building blocks of protein. The body makes tyrosine from another amino acid called phenylalanine.
In the diet, tyrosine can be eaten in dairy products, meats, fish, eggs, nuts, beans, oats, and wheat. The body uses tyrosine to make chemical messengers that are involved in conditions affecting the brain, such as mental alertness.
People most commonly use tyrosine in protein supplements for an inherited disorder called phenylketonuria (PKU). It is also used for alcohol use disorder, cocaine dependence, and memory and thinking skills, but there is no good scientific evidence to support most of these uses.
In the diet, tyrosine can be eaten in dairy products, meats, fish, eggs, nuts, beans, oats, and wheat. The body uses tyrosine to make chemical messengers that are involved in conditions affecting the brain, such as mental alertness.
People most commonly use tyrosine in protein supplements for an inherited disorder called phenylketonuria (PKU). It is also used for alcohol use disorder, cocaine dependence, and memory and thinking skills, but there is no good scientific evidence to support most of these uses.
Safety Safety definitions
When taken by mouth: Tyrosine is commonly consumed in foods. Tyrosine is possibly safe when taken as a medicine, short-term. It seems to be safe when taken in doses up to 150 mg/kg daily for up to 3 months. Some people experience side effects such as nausea, headache, fatigue, and heartburn.
When applied to the skin: Tyrosine is possibly safe when applied to the skin.
Thyroid disorders: The body uses tyrosine to make thyroxine, a thyroid hormone. Taking extra tyrosine might increase thyroxine levels too much. This could make hyperthyroidism and Grave's disease worse. If you have a thyroid disorder, don't take tyrosine supplements.
When applied to the skin: Tyrosine is possibly safe when applied to the skin.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if tyrosine is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.Thyroid disorders: The body uses tyrosine to make thyroxine, a thyroid hormone. Taking extra tyrosine might increase thyroxine levels too much. This could make hyperthyroidism and Grave's disease worse. If you have a thyroid disorder, don't take tyrosine supplements.
Effectiveness
NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
Effective Effectiveness definitions
- An inherited disorder that increases levels of phenylalanine in the blood (phenylketonuria or PKU). People with PKU are not able to process the amino acid phenylalanine. This amino acid is used by the body to make tyrosine. To prevent tyrosine levels from becoming too low, people with PKU are advised to consume medical foods that contain tyrosine and very little phenylalanine.
Possibly effective Effectiveness definitions
- Memory and thinking skills (cognitive function). Taking tyrosine by mouth might improve mental performance under stressful conditions.
- Memory. Taking tyrosine by mouth seems to improve memory during stressful situations.
Possibly ineffective Effectiveness definitions
- Athletic performance. Taking tyrosine by mouth before running or cycling doesn't seem to improve performance.
Dosing & administration
In the diet, tyrosine is found in dairy, meats, fish, eggs, nuts, beans, oats, and wheat. In supplements, tyrosine has most often been used by adults in doses of 100-300 mg/kg by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Interactions with pharmaceuticals
Levodopa
Interaction Rating=Moderate Be cautious with this combination.
Tyrosine might decrease how much levodopa the body absorbs. By decreasing how much levodopa the body absorbs, tyrosine might decrease the effects of levodopa. Do not take tyrosine and levodopa at the same time.
Thyroid hormone
Interaction Rating=Moderate Be cautious with this combination.
The body naturally produces thyroid hormones. Tyrosine might increase how much thyroid hormone the body produces. Taking tyrosine with thyroid hormone pills might cause there to be too much thyroid hormone. This could increase the effects and side effects of thyroid hormones.
Interactions with herbs & supplements
There are no known interactions with herbs and supplements.
Interactions with foods
There are no known interactions with foods.
Products
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Per 9.5 g (Tropical):
- L-tyrosine 1 g
- Nicotinamide (Vitamin B3) 25 mg
- Calcium pantothenate (Vitamin B5) 50 mg
- Co-methylcobalamin (Vitamin B12) 200 μg
- Magnesium bisglycinate 2 g equiv. magnesium 200 mg
- Thiamine hydrochloride (Vitamin B1) 25 mg
- Riboflavin 5-phosphate sodium (Activated B2) 25 mg equiv. riboflavin 18 mg
- Calcium hydrogen phosphate dihydrate 2.1 g equiv. calcium 500 mg
- Acetyl levocarnitine hydrochloride (Acetyl-L-carnitine) 1.2 g
- Ascorbic acid (Vitamin C) 500 mg
- Sodium phosphate dibasic anhydrous 250 mg equiv. sodium 81 mg
- Borax 13 mg equiv. boron 1.5 mg
- Potassium iodide 98 μg equiv. iodine 75 μg
- Selenomethionine 62.5 μg equiv. selenium 25 μg
- Zinc bisglycinate (Zinc amino acid chelate) 50 mg equiv. zinc 10 mg
400 g Tropical
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Per 6 g:
- L-tyrosine 1 g
- Magnesium citrate 1.23 g equiv. magnesium 200 mg
- Acetyl levocarnitine hydrochloride (Acetyl-L-carnitine) 1.18 g
- Bacopa monnieri ext. 225 mg
- Crocus sativus ext. 15 mg
- Calcium folinate (Activated folate) 347 µg equiv. folinic acid 250 µg
- Zinc amino acid chelate 25 mg equiv. zinc 5 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 7.8 mg equiv. pyridoxine 5 mg
- Mecobalamin (Vitamin B12) 500 µg
- Nicotinamide (Vitamin B3) 17.5 mg
Practitioner product
Per tablet:
- L-tyrosine 500 mg
- Potassium iodide 130.8 μg equiv. iodine 100 μg
- Selenomethionine 187.5 μg equiv. selenium 75 μg
- Inositol 300 mg
- Nicotinic acid (Vitamin B3) 5 mg
- Nicotinamide (Vitamin B3) 30 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 23.5 mg equiv. pyridoxine 15 mg
- Calcium folinate (Activated folate) 271 μg equiv. folinic acid 250 μg
- Hydroxocobalamin (Vitamin B12) 500 μg
- Thiamine hydrochloride (Vitamin B1) 12.7 mg equiv. thiamine 10 mg
- Zinc citrate dihydrate 30.77 mg equiv. zinc 10 mg
- Chromium nicotinate 120 μg equiv. chromium 15 μg
- Calcium pantothenate (Vitamin B5) 30 mg equiv. pantothenic acid 27.5 mg equiv. calcium 2.52 mg
- Riboflavin 5-phosphate sodium (Activated B2) 13.7 mg equiv. riboflavin 10 mg
- Withania somnifera ext. 24 mg
Practitioner product
Practitioner product
Per tablet:
- L-tyrosine 500 mg
- Potassium iodide 190 μg equiv. iodine 145 μg
- Selenomethionine 186 μg equiv. selenium 75 μg
- Zinc amino acid chelate 50 mg equiv. zinc 10 mg
- Retinol acetate 431.2 μg equiv. vitamin A 375 μgRE
- Ascorbic acid (Vitamin C) 50 mg
- d-alpha-Tocopheryl acid succinate 10.3 mg equiv. vitamin E 12.5 IU
- Bupleurum falcatum ext. 50 mg
- Schisandra chinensis ext. 187.5 mg
- Reduced glutathione 25 mg
- Cholecalciferol 7.5 μg equiv. vitamin D3 300 IU
Practitioner product
Per tablet:
- L-tyrosine 500 mg
- Potassium iodide 157 μg equiv. iodine 120 μg
- Selenomethionine 125 μg equiv. selenium 50 μg
- Rehmannia glutinosa ext. 67 mg
- Ascorbic acid (Vitamin C) 50 mg
- Thiamine hydrochloride (Vitamin B1) 50 mg
- Nicotinamide (Vitamin B3) 50 mg
- Pyridoxal 5-phosphate monohydrate (P5P) 15.67 mg equiv. pyridoxine 10 mg
- Pyridoxine hydrochloride (Vitamin B6) 25 mg equiv. pyridoxine 20.5 mg
- d-alpha-Tocopheryl acid succinate 10 mg equiv. vitamin E 12 IU
- Riboflavin 5-phosphate sodium (Activated B2) 4.11 mg equiv. riboflavin 3 mg
- Calcium folinate (Activated folate) 69 μg equiv. folinic acid 50 μg
- Cyanocobalamin (Vitamin B12) 1 mg
- Cholecalciferol 10 μg equiv. vitamin D3 400 IU
- Zinc ascorbate monohydrate 100 mg equiv. zinc 15 mg equiv. ascorbic acid 80.5 mg
- Calcium pantothenate (Vitamin B5) 75 mg equiv. pantothenic acid 68.7 mg equiv. calcium 6.3 mg
Practitioner product
Practitioner product
Per tablet:
- L-tyrosine 500 mg
- Potassium iodide 200 μg equiv. iodine 150 μg
- Selenomethionine 190 μg equiv. selenium 75 μg
- Zinc citrate dihydrate 15.58 mg equiv. zinc 5 mg
- Withania somnifera ext. 150 mg
- Rhodiola rosea ext. 25 mg
- Cholecalciferol 5 μg equiv. vitamin D3 200 IU
- d-alpha-Tocopheryl acid succinate 43 mg equiv. vitamin E 52 IU
- Ascorbic acid (Vitamin C) 100 mg
- Riboflavin 5-phosphate sodium (Activated B2) 13 mg equiv. riboflavin 10 mg
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Per 4 g (Mango Passionfruit):
- L-tyrosine 500 mg
- Acetyl L-carnitine (Acetyl-L-carnitine)
- Camellia sinensis
- Ascorbic acid (Vitamin C)
- Theobroma cacao powder 40 mg
- Pyridoxal 5-phosphate (P5P)
- Stevia rebaubiana
- Piper nigrum 5 mg
- Folate
- Methylcobalamin (Activated B12) 5 µg
- Hordeum vulgare 15 mg
- Gamma-Butyrobetaine (GBB) 15 mg
- Coffea arabica equiv. caffeine 150 mg
- Alpinia galanga powder 150 mg
- Orthosilicic acid (Silica)
- Citric acid anhydrous
- Xanthan gum
- Chromium picolinate
- Natural flavours
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Per 4 g (Grape):
- L-tyrosine 500 mg
- Camellia sinensis 200 mg
- Coffea canephora 150 mg
- Theobroma cacao 50 mg
- Gamma-Butyrobetaine (GBB) 50 mg
- Polyphenolic fulvic minerals 10 mg
- Acetyl L-carnitine (Acetyl-L-carnitine) 1 g
- Carnitine tartrate 500 mg
- Citrus aurantium 60 mg
- Aframomum melegueta 25 mg
- Chromium picolinate 200 µg
- Natural flavours
- Malic acid
- Stevia rebaubiana
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Per capsule:
Practitioner product
Per capsule:
- L-tyrosine 350 mg
- Potassium iodide 196 μg equiv. iodine 149.84 μg
- Selenomethionine 186.5 μg equiv. selenium 74.6 μg
- Withania somnifera ext. 300 mg
- Zinc citrate dihydrate 31.15 mg equiv. zinc 10 mg
- Cholecalciferol 12.5 μg equiv. vitamin D3 500 IU
- Retinol acetate (Vitamin A) 344.1 μg equiv. vitamin A 300 μg RE equiv. vitamin A 1000 IU
Practitioner product
Per 9.8 g (Tropical):
- L-tyrosine 250 mg
- Magnesium bisglycinate 3 g equiv. magnesium 300 mg
- Taurine 1.5 g
- Myo-inositol 1 g
- Calcium ascorbate dihydrate (Vitamin C) 605 mg equiv. ascorbic acid 500 mg
- Calcium pantothenate (Vitamin B5) 50 mg
- Pyridoxine hydrochloride (Vitamin B6) 25 mg equiv. pyridoxine 15.97 mg
- Chromic chloride hexahydrate 513 μg equiv. chromium 100 μg
- Mecobalamin (Vitamin B12) 200 μg
- Levomefolate calcium (Activated folate) 216 μg equiv. levomefolic acid 200 μg
- Potassium iodide 98 μg equiv. iodine 75 μg
- Zinc bisglycinate (Zinc amino acid chelate) 30 mg equiv. zinc 6 mg
- Selenomethionine 62.5 μg equiv. selenium 25 μg
Practitioner product
Per tablet:
- L-tyrosine 250 mg
- Crocus sativus ext. 17.5 mg
- Withania somnifera ext. 250 mg
- Levomefolate calcium (Activated folate) 216 μg equiv. levomefolic acid 200 μg
- Pyridoxal 5-phosphate monohydrate (P5P) 31.9 mg equiv. pyridoxine 20 mg
- Co-methylcobalamin (Vitamin B12) 75 μg
- Zinc amino acid chelate 60 mg equiv. zinc 12 mg
Practitioner product
Per capsule:
- L-tyrosine 200 mg
- Ascorbic acid (Vitamin C) 40 mg
- Zinc citrate dihydrate 9.35 mg equiv. zinc 3 mg
- Rehmannia glutinosa ext. 50 mg
- Eleutherococcus senticosus ext. 40 mg
- Withania somnifera ext. 80 mg
- Thiamine hydrochloride (Vitamin B1) 10 mg equiv. thiamine 8.9 mg
- Riboflavin (Vitamin B2) 10 mg
- Nicotinamide (Vitamin B3) 15 mg
- Calcium pantothenate (Vitamin B5) 75 mg equiv. pantothenic acid 68.7 mg
- Pyridoxine hydrochloride (Vitamin B6) 15 mg equiv. pyridoxine 12.3 mg
- Magnesium phosphate pentahydrate 48.4 mg equiv. magnesium 10 mg
- Potassium iodide 98 μg equiv. iodine 75 μg
- Chromium nicotinate 133.3 μg equiv. chromium 16 μg
- Selenomethionine 37.5 μg equiv. selenium 15 μg
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This monograph was last reviewed on 12/04/2024 10:00:00 and last updated on 07/02/2022 23:40:56. Monographs are reviewed and/or updated multiple times per month and at least once per year.
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Natural Medicines rates safety based on scientific evidence according to the following scale: Likely Safe, Possibly Safe, Possibly Unsafe, Likely Unsafe, Unsafe, and Insufficient Evidence to Rate. For more information about Natural Medicines’ Safety Rating System, click here.
The Natural Medicines Effectiveness Ratings are assigned for specific indications. A product might be rated "Possibly Effective" for one condition, but be rated "Likely Ineffective" for another condition, depending on the evidence. For more info click here.
